Background And Aim: Previous nursing studies have explored advocacy from several perspectives, including examining its definition, analyzing the concept, developing theory based on concept analysis, and developing scales to assess advocacy in practice. This study aims to determine the reliability and validity of a scale to assess the advocacy practices of public health nurses (PHNAP) working in extra-hospital and community settings in Italy.
Methods: A validation study was conducted. After the translation phase, the questionnaire was administered to a convenience sample of nurses in various municipalities in Italy. Reliability was assessed by calculating the alpha coefficient. To assess construct validity, exploratory and confirmatory factor analyses were conducted. Data was collected between November and December 2024.
Results: A total of 457 questionnaires were analyzed. The overall Cronbach's alpha coefficient was 0.926, and factors 1 through 5 were 0.911, 0.812, 0.836, 0.869, and 0.895, respectively. Regarding the criterion-related validity results, the correlation coefficient between the total score and the score on the scale for the practical competence of PHNs in Italy exhibited a moderate correlation (r = 0.428; lt; 0.01). The scale comprised 27 items divided into five factors: "Raising awareness of the challenging situation faced by disadvantaged individuals," "Empowering disadvantaged individuals to improve their situation autonomously," "Establishing a foundation in local governments and community groups of disadvantaged individuals for advocacy initiatives," "Working toward policy changes," and "Collaborating with stakeholders and organizations to enhance the effectiveness of activities." In the confirmatory factor analysis; that the chi-square degree of freedom ratio (χ2 /df), the goodness-of-fit index (GFI), the root mean square of approximate error (RMSEA), the value-added fitting index (IFI) and the comparative fitting index (CFI) were determined to be 2.765, 0.849, 0.065, 0.819 and 0.824, respectively.
Conclusion: The scale designed in this study is valid and reliable for use in the Italian context and it is applicable in various contexts where PHNs also support disadvantaged populations.
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Diagn Cytopathol
March 2025
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.
Introduction: Soft tissue lesions encompass a diverse category of diseases from benign to malignant, and their morphology might overlap; therefore, accurate categorization is needed to approach the reporting of soft tissue cytology. The cytology of these lesions is helpful in detecting the features of malignancy, which helps in guiding further management. In this study, we applied the proposed IAC-IARC-WHO cytopathology system to assess the risk of malignancy (ROM) and diagnostic accuracy (DA) for the determination of its clinical and diagnostic utility.
View Article and Find Full Text PDFChronic Stress (Thousand Oaks)
March 2025
Laboratorio de Neurociencias y Psicología Experimental. Área de Farmacología. Facultad de Ciencias Médicas, Universidad Nacional de Cuyo, Mendoza, Argentina.
Generalized anxiety has significantly increased in the general population during and after the COVID-19 pandemic, highlighting the need for rapid screening tools. In this context, the present study analyzed the psychometric properties and internal consistency of the Generalized Anxiety Disorder Scale (GAD-7) in healthcare workers and the general population in Latin America. A cross-sectional e-health study was conducted, surveying 11,279 Latin Americans online using snowball sampling.
View Article and Find Full Text PDFInt J Chron Obstruct Pulmon Dis
March 2025
Department of General Medical, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Purpose: The miR-125a-5p has been reported influence the development of lung cancer, however, the link between it and chronic obstructive pulmonary disease (COPD) is still not well understood. Hence, this study was designed to investigate the molecular pathway by which miR-125a-5p related biomarkers were involved in COPD.
Patients And Methods: The differentially expressed genes (DEGs) and module genes related to COPD in GSE100153 were screened out by differential analysis and weighted gene co-expression network analysis, respectively.
Front Cell Infect Microbiol
March 2025
Department of Clinical Laboratory, Guangzhou Institute of Respiratory Health, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Laboratory, The First Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Objective: Bloodstream infections(BSIs) caused by carbapenem-resistant (CRAB) have a high mortality rate due to the high levels of drug resistance. There is an urgent need to establish a sensitive and accurate detection method to rapidly detect CRAB in BSIs.
Methods: A new method was developed based on fluorescence quantitative PCR (qPCR) targeting the specific region of 16sRNA and OXA-23 gene from CRAB.
F1000Res
March 2025
Department of Mathematics, Bahir Dar University, Bahir Dar, Amhara, Ethiopia.
Background: This research investigates the unsteady magnetohydrodynamic (MHD) flow, heat, and mass transfer of tangent hyperbolic ternary hybrid nanofluids over a permeable stretching sheet. The study considers three types of nanoparticles-aluminum oxide (Al₂O₃), copper (Cu), and titanium oxide (TiO₂)-dispersed in a base fluid of ethylene glycol (C₂H₆O₂). This ternary hybrid nanofluid (Al₂O₃-Cu-TiO₂/C₂H₆O₂) has potential applications in cooling systems, biomedical uses for targeted drug delivery and hyperthermia treatments, heat exchangers, and polymer processing techniques like extrusion and casting.
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