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Effects of reading augmented reality storybook versus normal storybook reading on preoperative fear and anxiety levels of children in the age group of 7-12 years: A randomized controlled trial.
J Pediatr Urol
February 2025
Manisa Celal Bayar University, Faculty of Health Sciences, Department of Nursing, Turkey. Electronic address:
Aim And Objectives: In the preoperative period, non-pharmacological methods such as multimedia applications and visual and audio technological tools are used to reduce children's fear and anxiety levels and to distract their attention to create a more enjoyable experience. One of these innovative technologies having attracted attention recently is augmented reality technology. The study was aimed investigating the effects of reading an augmented reality storybook on fear and anxiety levels of children in the age group of 7-12 years in the preoperative period.
View Article and Find Full Text PDFSynthesis, cytotoxicity and HQSAR study of amides-fused isosteviol derivatives as potential anti-colorectal cancer agents.
Fitoterapia
March 2025
Innovative Practice Platform for Research-oriented Teaching of Natural Product Resources Development and Application, School of Food Science and Chemical Engineering, Zhengzhou University of Technology, Zhengzhou, Henan 450044, China.
A series of novel amide-fused isosteviol derivatives were designed and synthesized. Their cytotoxicities in vitro against HCT-116 cells were screened. The preliminary bioassays indicated that most of the title compounds exhibited noteworthy cytotoxicity.
View Article and Find Full Text PDFExtraction and Characterization of Aceh Bovine Bone-Derived Hydroxyapatite for Applications in Dentistry.
Eur J Dent
March 2025
Department of Dental Material, Faculty of Dentistry, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Objective: Bone grafts derived from natural hydroxyapatite (HA) are increasingly being explored because they are more economical in terms of production costs compared with commercial HA. HA can be obtained from local cattle slaughter waste in Aceh, Indonesia, which has not been widely studied for its potential for dental applications. This study examines the synthesis and characterization of bovine HA (BHA) derived from Aceh cattle femur through calcination for applications in dentistry.
View Article and Find Full Text PDFOptimizing the Surface Quality of L-PBF Ti6Al4V ELI Alloy via Electropolishing and Its Effect on Corrosion Resistance for Dental Applications.
Eur J Dent
March 2025
Department of Prosthodontics, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.
Objectives: The Ti6Al4V ELI alloy produced via laser powder bed fusion (L-PBF) has attracted interest for use in dental applications. However, surface finishing is an important property that can be managed by various methods. The purpose of this study was to investigate the effects of electropolishing (EP) on the surface roughness and corrosion resistance of L-PBF Ti6Al4V ELI alloy.
View Article and Find Full Text PDFEffective transcatheter intracoronary delivery of mRNA-lipid nanoparticles targeting the heart.
J Control Release
March 2025
Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Osaka, Japan; Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Osaka University, Osaka, Japan. Electronic address:
Messenger RNA (mRNA) has great potential to provide innovative medical solutions in the treatment of heart failure. Although lipid nanoparticles (LNPs) are an established mRNA delivery system, effectively delivering LNPs to the heart remains a significant challenge. Here, we evaluated the efficacy of transcatheter intracoronary (IC) administration compared to intravenous (IV) and intramyocardial (IM) administration in normal and ischemia-reperfusion (I/R) model rabbit hearts using LNPs encapsulating Firefly Luciferase (FLuc) mRNA.
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