Giant cell arteritis (GCA) is the most common of the large vessel vasculitides, with [F] fluorodeoxyglucose (FDG) PET/CT indicated for evaluation of suspected large vessel involvement. Advances in PET/CT technology, particularly with digital PET, have significantly improved the assessment of cranial artery involvement in GCA. Recent guidelines have been updated to incorporate [F]FDG PET/CT imaging in the diagnosis of GCA. This review article provides a practical guide to the most recent recommendations regarding PET/CT study indications, image acquisition and interpretation criteria for GCA, while discussing potential pitfalls and future research directions in the field.
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http://dx.doi.org/10.23736/S1824-4785.25.03611-8 | DOI Listing |
Background: Neuroendocrine carcinomas (NECs) are rare tumors from hormone-secreting neuroendocrine cells, often within the gastrointestinal tract. The authors report what is, to their best knowledge, the first case of a small intestine NEC metastasizing to the temporomandibular joint (TMJ).
Case Description: A 60-year-old man came to the oral medicine, oncology, and orofacial pain clinic with a chief concern of left-sided jaw pain.
Rheumatology (Oxford)
March 2025
Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch, Berlin, Germany.
Objectives: Both imaging and temporal artery biopsy (TAB) are utilized to confirm a suspected diagnosis of giant cell arteritis (GCA). What are the advantages of imaging over TAB?
Methods: This article is based on a debate presented at the 21st Vasculitis Meeting, discussing whether imaging or TAB with histology should be the primary diagnostic method for suspected GCA.
Results: A suspected diagnosis of GCA should be confirmed or excluded either through imaging or histology.
Rheumatology (Oxford)
March 2025
Rheumatology Department, Health New Zealand, Auckland, New Zealand.
The session on 'Diagnosis and Classification of Vasculitis' featured six oral presentations covering various aspects of vasculitis diagnosis and classification. The application of the Ankara criteria for IgA vasculitis in adults was evaluated, finding that while the criteria showed good sensitivity, their specificity was insufficient, suggesting the need for refinement. A clustering approach to classifying ANCA-associated vasculitis (AAV) identified five distinct clusters, which improved prediction of disease outcomes.
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March 2025
Department of Rheumatology, Austin Health, Heidelberg, VIC, Australia.
Modern imaging including ultrasound, MRI and PET have all played a pivotal role in characterizing the distinctive musculotendinous pathology that is now recognized to define PMR. Each of these modalities offers inherent advantages and disadvantages relative to availability, cost and radiation exposure, although MRI and hybrid PET/CT are particularly capable of detecting highly sensitive and specific findings, and thus should be considered reliable tools for PMR diagnosis in everyday clinical practice. By contrast, the utility of imaging for monitoring disease activity and predicting long-term clinical outcomes represents areas of ongoing research interest.
View Article and Find Full Text PDFRheumatology (Oxford)
March 2025
Department of General Internal Medicine, UZ Leuven, Leuven, Belgium.
The breakout session "Imaging in Disease Assessment" featured six abstracts on imaging advancements for vasculitis. Disease extent on cranial MRI and its association with visual complications in giant cell arteritis (GCA) was evaluated, introducing the Propensity for Enhancement for GCA (P EG) score to assess inflammation. Predictors of remission and relapse in chronic periaortitis were analyzed, suggesting the potential for tailored treatment approaches.
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