Diagnosis of spondylodiscitis remains a challenge for clinicians. It results from various causative agents and conditions that can be challenging to identify. Prompt and appropriate treatment are necessary to prevent long-term irreversible complications and sequelae. The diagnosis of spondylodiscitis often constitutes a major challenge for the clinicians, and relies on the combination of clinical, laboratory and imaging findings. Various imaging techniques can be used for the workup of spondylodiscitis, with magnetic resonance imaging and 18-fluoro-deoxy-glucose positron emission tomography, combined with a CT being the most commonly used in daily practice. The aim of this review is to provide general information about indications and protocols for [F]FDG PET/CT imaging in spinal infections, focusing on spondylodiscitis, in adults.
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Spondylodiscitis.
Q J Nucl Med Mol Imaging
March 2025
Department of Diagnostic Imaging, University Hospital of Fuenlabrada, Fuenlabrada, Spain.
Diagnosis of spondylodiscitis remains a challenge for clinicians. It results from various causative agents and conditions that can be challenging to identify. Prompt and appropriate treatment are necessary to prevent long-term irreversible complications and sequelae.
View Article and Find Full Text PDFPercutaneous pedicle screw fixation in the surgical treatment of monosegmental pyogenic spondylodiscitis.
J Orthop Surg Res
March 2025
Department of Orthopedics, 5th Affiliated Hospital, Lishui Municipal Central Hospital, Wenzhou Medical College, No. 289 Kuocang Road, Lishui, 323000, China.
Objective: The study assessed the efficacy of percutaneous pedicle screw fixation (PPSF) as a treatment approach for monosegmental pyogenic spondylodiscitis (PS), particularly in patients with compromised health conditions that reduce their ability to endure extensive surgical procedures.
Methods: From January 2019 and December 2021, a total of 38 patients with PS who underwent PPSF at our hospital were included in the study. Clinical outcomes were assessed using physical examinations, serological tests, Visual Analog Scale (VAS) scores, Oswestry Disability Index (ODI) scores, and imaging assessments.
Case series of spondylodiscitis and a brief review of the literature.
Infect Dis (Lond)
March 2025
Department of Infectious Diseases, Odense University Hospital, Odense, Denmark.
Introduction: is the most frequent fungal organism causing vertebral spondylodiskitis. Given limited research, this study aimed to describe patient characteristics, treatment, and outcomes of the spondylodiscitis patients in Southern Denmark using a case series and literature review.
Methods: We conducted a retrospective review of all consecutive patients treated for infectious spondylodiscitis during 2009-2023 at the Department of Infectious Diseases, Odense University Hospital, Denmark.
Clinical and demographic characteristics of spondylodiscitis in a Mexican population: A retrospective study.
Rev Argent Microbiol
February 2025
Department of Neurosurgery, South Central High Specialty Hospital, Tlalpan, Mexico City, Mexico; Department of Neurosurgery, The American British Cowdray Medical Center, Cuajimalpa, Mexico City, Mexico.
The aim of this study was to identify the clinical and demographic characteristics of patients with a confirmed diagnosis of spondylodiscitis through microbiological cultures. A descriptive, observational, and retrospective study was conducted. Patients were included based on clinical and radiological evidence of vertebral infection, unspecified discitis, and/or positive microbiological cultures consistent with spondylodiscitis.
View Article and Find Full Text PDFPlasma Microbial Cell-free DNA Sequencing for the Detection of Kingella kingae Pediatric Spinal Infections.
Pediatr Infect Dis J
February 2025
Clinical Microbiology Laboratory and Pediatric Infectious Disease Unit, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Background: Diagnosis of Kingella kingae skeletal system infections is made challenging by the microbe's fastidious nature. Detection and quantification of circulating microbial cell-free DNA (mcfDNA) in plasma by the Karius Test, a commercial metagenomic sequencing test, may offer promise in diagnosing pediatric spinal infections caused by difficult-to-culture organisms such as K. kingae.
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