Female adnexal tumor of presumed Wolffian origin (FATWO) is a rare gynecologic neoplasm favored to arise from mesonephric (Wolffian) remnants. Although most tumors are benign, rare recurrences have been reported. Herein, we present a case of a 65-year-old female with incidental peritoneal lesions detected on routine ultrasound that morphologically and immunohistochemically were diagnostic of FATWO. Review of her medical history uncovered a remote history (>30 years) of a para-ovarian cystectomy, which was punctured intraoperatively. Slide review confirmed the diagnosis of FATWO, thereby suggesting iatrogenic dissemination from the original procedure. This report highlights the importance of a thorough review of the medical record when encountering a nonprototypical location for a distinctive tumor. In addition, the slow-growing nature of these lesions, as well as the absence of atypical histologic features, further contributes to the hypothesis that the majority of FATWOs are benign.
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http://dx.doi.org/10.1097/PGP.0000000000001103 | DOI Listing |
Sci Rep
March 2025
Department of Obstetrics and Gynecology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Chronic endometritis (CE) and endometrial dysbiosis (ED) are major causes of recurrent implantation failure (RIF). CE is diagnosed via hysteroscopy or the endometrial CD138 test; ED is examined using endometrial microbiome testing with next-generation sequencing. ED is characterized by a reduction in Lactobacillus species.
View Article and Find Full Text PDFInt J Gynecol Pathol
January 2025
Department of Pathology, University of Chicago, Chicago, Illinois.
Female adnexal tumor of presumed Wolffian origin (FATWO) is a rare gynecologic neoplasm favored to arise from mesonephric (Wolffian) remnants. Although most tumors are benign, rare recurrences have been reported. Herein, we present a case of a 65-year-old female with incidental peritoneal lesions detected on routine ultrasound that morphologically and immunohistochemically were diagnostic of FATWO.
View Article and Find Full Text PDFCureus
February 2025
Department of Plastic Surgery, Dermatology and Plastic Surgery of Arizona, Tucson, USA.
Chondroid syringomas are rare adnexal neoplasms composed of epithelial and mesenchymal components, posing diagnostic challenges due to their diverse histological features. We report an atypical presentation of an apocrine mixed tumor in a 51-year-old female patient who presented with a 0.7 cm firm, flesh-colored nodule on the right lateral cutaneous lip.
View Article and Find Full Text PDFCNS Neurosci Ther
March 2025
Department of Neurology, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.
Background: Numerous studies have demonstrated the significant role of Akkermansia muciniphila (A. muciniphila) in enhancing host immune responses and metabolic functions. However, its increased presence in multiple sclerosis (MS) patients has led to a focus on the relationships between A.
View Article and Find Full Text PDFTaiwan J Obstet Gynecol
March 2025
Fundación Cardiovascular de Colombia, Piedecuesta, Santander, Colombia.
Objective: Describe a clinical case of a patient with Herlyn Werner Wunderlich Syndrome in whom an accurate diagnosis was not made during menarche due to failures in her care and poor diagnostic suspicion.
Case Report: Female patient, 21 years old, without medical history, menarche at 12 years of age, with hypermenorrhea and recurrent urinary tract infection. Patient with uterus-dependent mass associated with left renal agenesis, laparotomy was performed with the finding of a didelphic uterus and compensatory hypertrophy of the right kidney, uterine growth with widening of the endometrial cavity and right adnexal septated cyst, absence of left kidney, bicornuate uterus, bicollis, distended vagina and hematocolpos with these findings, clinical genetics considers Herlyn Werner Wunderlich Syndrome.
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