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Synthesis, Characterization, and Docking Studies of Some New Chalcone Derivatives to Alleviate Skin Damage Due to UV Light.
Molecules
February 2025
Department of Pharmaceutical Chemistry, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu 333053, India.
Increasing cases of sunburn is one of the serious problems across the globe. In this connection, there is an urgent requirement for some effective sun screening agents. In the search for the same, nanoemulsions of some new synthesized and characterized chalcone derivatives were prepared and evaluated in vitro and in vivo.
View Article and Find Full Text PDFEnhancing Thin Film Properties of Chitosan-Collagen Biocomposites Through Potassium Silicate and Tannic Acid Integration.
Polymers (Basel)
February 2025
Department of Cell Biology and Imaging, Institute of Zoology and Biomedical Research, Faculty of Biology, Jagiellonian University in Kraków, Gronostajowa 9, 30-387 Kraków, Poland.
Chitosan and collagen are natural polymers widely used in biomaterials science; however, their inherent low stability and solubility present several challenges to obtain formulations suitable for potential clinical applications. In this study, tannic acid (TA) was employed as a cross-linker to improve the properties of thin films made from chitosan and collagen. In addition, potassium silicate (PS) was added as an inorganic filler, to produce innovative biocomposite films.
View Article and Find Full Text PDFThoracodorsal Artery Perforator Diameter and Flow Velocity Correlate with Muscle Thickness.
J Reconstr Microsurg
March 2025
Department of Hand, Plastic, Reconstructive and Burn Surgery, BG Unfallklinik Tuebingen, Eberhard Karls University Tuebingen, Tuebingen, Germany.
Background: The thoracodorsal artery perforator (TDAP) flap is a versatile pedicled and free flap with low donor site morbidity and a relatively thin skin paddle. Physical patient characteristics may influence interindividual differences in perforator characteristics and, therefore, help to estimate the safety of the TDAP flap.
Methods: Dynamic infrared thermography and color duplex ultrasound were applied to assess the TDAP diameter, peak systolic velocity (PSV), end-diastolic velocity, resistance index, and thickness of the latissimus dorsi muscle and the subcutaneous tissue bilaterally in 25 subjects.
Wearable transdermal drug delivery system controlled by wirelessly powered acoustic waves.
J Control Release
March 2025
Faculty of Engineering and Environment, Northumbria University at Newcastle, Newcastle upon Tyne, NE1 8ST, UK. Electronic address:
Transdermal drug administration offers an alternative route for drug delivery through the skin, and surface acoustic wave (SAW) technology has recently emerged as a promising approach to enhance this process. However, conventional cable-connected SAW control units face several challenges, including inconvenience, poor wearability, limited miniaturization and integration, and restricted reusability. This study introduces a wireless-powered transport strategy for the transdermal delivery of large drug molecules using a thin-film-based SAW platform.
View Article and Find Full Text PDFThin Skin in Cushing's Syndrome.
N Engl J Med
March 2025
Lausanne University Hospital, Lausanne, Switzerland.
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