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http://dx.doi.org/10.1111/1346-8138.17677 | DOI Listing |
Dermatol Surg
March 2025
All authors are affiliated with the Dermatology Department, Cairo University, Cairo, Egypt.
Background: Alopecia areata (AA) is a common autoimmune disorder with significant psychosocial burden. Intralesional corticosteroid (ILCS) injection is considered the main line of management. More tolerable treatment methods with less side effects are needed.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
January 2025
Department of ENT, Government Medical College, Gandhinagar, Kottayam, India.
A systematic review of literature on treatment modalities available with respect to efficacy, complications and recurrences so as to guide the clinician to better treat this enigmatic condition. A systematic search of PubMed, Google Scholar, Ovid and Cochrane databases. Articles in English that described or compared treatment were included.
View Article and Find Full Text PDFActa Trop
March 2025
Post-graduation Program in Nanotechnology Engineering - PENt, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address:
Intralesional (IL) treatment of cutaneous leishmaniasis with pentavalent antimonials has greatly reduced the systemic toxicity imposed by the conventional intramuscular and intravenous injections. Nevertheless, therapeutic failure with antimonials can occur due to drug resistance and/or short retention in the inflamed skin. Here we evaluated the safety and efficacy of IL treatment with injectable amphotericin B (AmB), a powerful antileishmanial drug that is less prone to drug resistance, but due to its amphiphilic nature is formulated with the ionic detergent sodium deoxycholate (Deox).
View Article and Find Full Text PDFMicrosyst Nanoeng
March 2025
Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, School of Biomedical Engineering, Shenzhen Campus of Sun Yat-Sen University, Shenzhen, 518107, PR China.
Hypertrophic scar (HS) is a plaque fibrous and indurated dermal lesion that may cause physical, psychological, and cosmetic challenges for patients. Intralesional injection of triamcinolone acetonide (TA) is commonly used in clinical practice, which cause unbearable pain and uneven drug delivery within HS tissue. Herein, we developed a paper battery powered iontophoresis-driven microneedles patch (PBIMNP) for self-management of HS.
View Article and Find Full Text PDFJ Dermatol
March 2025
Department of Dermatology, Japanese Red Cross Saitama Hospital, Saitama, Japan.
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