Background: The incidence of kidney stones has been rising globally, particularly among the elderly. This study aims to determine the prevalence of kidney stones and its associated factors in Iran.
Methods: This cross-sectional study was conducted using the data collected in the first phase of Ardakan Cohort Study on individuals aged 50 years and above, in the Yazd province, Iran. Baseline data was collected using a comprehensive checklist and kidney stone occurrence was ascertained through participants' self-reported response to the question "Have you ever been diagnosed with kidney stones?" Logistic regression analysis was used due to the binary nature of the outcome.
Results: Period prevalence of kidney stone was 22.79 (95% CI=19.41 to 24.12). Thus, out of the total sample of 4,884 individuals, 1113 participants had a history of kidney stones. Among these, 412 (37%) were female and 701 (63%) were male. Significant associations were observed between a history of kidney stones and factors such as self-reported poor health, alcohol consumption, dysuria, higher education level, male gender, and presence of calcium oxalate crystals.
Conclusion: This study shows the high prevalence of kidney stones compared to other studies. Considering the relationship between kidney stones and some preventable disorders in the elderly, such as high blood pressure and alcohol consumption, it seems that paying attention to kidney stone disorders can be part of preventive health and treatment interventions for this population group.
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http://dx.doi.org/10.34172/aim.33337 | DOI Listing |
Front Endocrinol (Lausanne)
March 2025
Department of Urology, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Background: Kidney stones are a chronic metabolic disorder. The cardiometabolic index (CMI) is a new and easily accessible measure used to assess metabolic status. However, the relationship between CMI and the incidence of kidney stones remains unclear.
View Article and Find Full Text PDFJ Nanobiotechnology
March 2025
Department of Urology, Renmin Hospital of Wuhan University, No. 238 Jiefang Road, Wuchang District, Wuhan, Hubei, 430060, P.R. China.
Background: Calcium oxalate (CaOx) crystals are known to cause renal injury and trigger inflammatory responses. However, the role of exosome-mediated epithelial-macrophage communication in CaOx-induced kidney injury remains unclear.
Methods: To identify key molecules, miRNA sequencing was conducted on exosomes derived from CaOx-treated (CaOx-exo) and control (Ctrl-exo) epithelial cells, identifying miR-93-3p as significantly upregulated.
J Endourol
March 2025
Progressive Endourological Association for Research and Leading Solutions (PEARLS), Paris, France.
Urolithiasis guidelines still rely on the maximum stone diameter to propose treatment strategy, although this measure is known to have many pitfalls. Stone volume (SV) could represent a more accurate measurement, helping to plan the treatment or follow-up. Various methods to measure SV have been proposed.
View Article and Find Full Text PDFChemistry
March 2025
Ludwig-Maximilians-Universität München: Ludwig-Maximilians-Universitat Munchen, Geo- und Umweltwissenschaften, GERMANY.
Crystal growth of calcium oxalate hydrates (COM: calcium oxalate monohydrate; COD: -dihydrate; COT: -trihydrate) is a specific example of biomineralization due to their harmful role as kidney/urinary stones. In this work, the biomimetic growth of calcium oxalate hydrates has been achieved using double diffusion technique in agar gel matrix. In-vitro experimental models for the growth of calcium oxalates can give valuable information on the formation of kidney/urinary stones.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Urology, Faculty of Medicine, Cukurova University, 01330, Adana, Turkey.
PCNL, a minimally invasive surgical technique for kidney stone removal, relies on achieving stone-free status, which various scoring systems aim to predict. This study assesses the predictive accuracy of the Clinical Research Office of the Endourological Society (CROES) and Guy's Stone Score (GSS) systems in determining stone-free rates following percutaneous nephrolithotomy (PCNL) in pediatric patients. A retrospective analysis was conducted on 580 pediatric patients who underwent PCNL at Çukurova University Urology Clinic between January 2007 and March 2024.
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