With the rapid advancement of Internet of Things (IoT) technology, the volume of sensor data collection has increased significantly. These data are typically presented in the form of time series, gradually becoming a crucial component of big data. Traditional time series analysis methods struggle with complex patterns and long-term dependencies, whereas deep learning technologies offer new solutions. This study introduces the U-TSS, a U-net-based sequence-to-sequence fully convolutional network, specifically designed for one-dimensional time series segmentation tasks. U-TSS maps input sequences of arbitrary length to corresponding sequences of class labels across different temporal scales. This is achieved by implicitly classifying each individual time point in the input time series and then aggregating these classifications over varying intervals to form the final prediction. This enables precise segmentation at each time step, ensuring both global sequence awareness and accurate classification of complex time series data. We applied U-TSS to geomagnetic field observation data for the detection of high-voltage direct current (HVDC) interference events. In experiments, U-TSS achieved superior performance in detecting HVDC interference events, with accuracies of 99.42%, 94.61%, and 95.54% on the training, validation, and test sets, respectively, outperforming state-of-the-art models in accuracy, precision, recall, F1-score, and AUC. Our code can be accessed openly in the GitHub repository at https://github.com/wangmengyu1/U-TSS.
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http://dx.doi.org/10.7717/peerj-cs.2678 | DOI Listing |
Ren Fail
December 2025
Department of Nephrology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.
Background: IgA nephropathy (IgAN) presents a challenging spectrum of outcomes, often complicated by intrarenal arterial/arteriolar lesions (IALs) in affected individuals. Despite their clinical relevance, existing criteria for classifying and assessing the severity of these lesions remain undefined. This study aimed to establish semi-quantitative assessment criteria for grading IALs and to evaluate their prognostic significance in patients with IgAN.
View Article and Find Full Text PDFChemphyschem
March 2025
Universität Siegen, Physikalische Chemie, Adolf-Reichwein-Str. 2, 57076, Siegen, GERMANY.
Organic-inorganic halocuprates(I) form a promising class of light-emitting materials with high photoluminescence (PL) quantum yield. However, the understanding of their emission properties and the PL mechanism is still limited. Here, we investigate thin films of bis(tetrapropylammonium) hexa-µ-bromo-tetrahedro-tetracuprate(I), [N(C3H7)4]2[Cu4Br6], which has a zero-dimensional (0D) molecular salt structure containing [Cu4Br6]2- ions.
View Article and Find Full Text PDFAm J Geriatr Psychiatry
February 2025
Department of Psychiatry (AJCS, EJG), Leiden University Medical Center, Leiden, The Netherlands; Health Campus The Hague (EJG), Department of Public Health & Primary Care, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:
Background: The prevalence of depressive symptoms, apathy, and cognitive decline increases with age. Understanding the temporal dynamics of these symptoms could provide valuable insights into the early stages of cognitive decline, allowing for more timely and effective treatment and management.
Methods: Participants from the Prevention of Dementia by Intensive Vascular Care (preDIVA) trial cohort with baseline and ≥3 follow-up measurements were included, with a median of 7.
Res Social Adm Pharm
March 2025
Department of Primary Care and Medical Education, Institute of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. Electronic address:
Background: Deprescribing by physicians based on the suggestions of community pharmacists is useful to ensure medication safety. Pharmacist-led deprescribing is not always implemented smoothly because of communication gaps between physicians and pharmacists. Our previous study found that assertiveness, as a communication style, is associated with pharmacist-initiated prescription changes for medication safety; however, its association with community pharmacist-led deprescribing is unclear.
View Article and Find Full Text PDFBr J Anaesth
March 2025
Department of Surgical Interventional Sciences, McGill University Health Center, Montreal, QC, Canada; Department of Anesthesia, McGill University, Montreal, QC, Canada; Department of Surgery, McGill University, Montreal, QC, Canada. Electronic address:
Background: In the UK, total intravenous anaesthesia (TIVA) is used in 25% of general anaesthetics and is gaining traction because of its lower environmental impact and effectiveness in reducing postoperative nausea and vomiting (PONV). Although meta-analyses have compared TIVA and inhalational anaesthesia (IA), the optimal delivery method-manual infusion or target-controlled infusion (TCI)-remains underexplored. This review addresses this gap, leveraging the rapidly growing body of evidence to guide optimal anaesthetic practice.
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