Introduction: It is essential that diagnostic tests for evaluating respiratory muscles have proven reliability and validity. This study aims to synthesize studies that evaluated the psychometric properties of volitional tests used to measure respiratory muscle strength and endurance.
Methods: A systematic literature search was conducted in MEDLINE/PubMed, LILACS, Cochrane Central Register of Controlled Trials, Scopus and SciELO. Primary studies that evaluated the reliability and validity of volitional tests to measure respiratory muscle strength and endurance were included. The quality of the included studies was assessed using the Critical Appraisal Tool (CAT).
Results: Twenty-eight studies were included in this review, describing the psychometric properties of eight different approaches to measuring respiratory muscle strength and endurance. Respiratory muscle strength and endurance were assessed using static maximal inspiratory pressure, static maximal expiratory pressure, dynamic maximal inspiratory pressure, sustained maximal inspiratory pressure, nasal inspiratory pressure, manual respiratory muscle measurements, and maximal incremental inspiratory muscle performance. Overall, the studies included were of good methodological quality. Data related to validity and reliability showed excellent results for the maximum inspiratory pressure and maximum expiratory pressure, with maximum ICC values of 0.979 (CI 0.947-0.991) and 0.989 (CI 0.022-0.001), respectively. Other tests evaluated did not present high reliability and validity.
Conclusion: This review concluded that volitional tests vary in reliability for measures of respiratory muscle strength and endurance. The more traditional ones, such as maximum inspiratory pressure and maximum expiratory pressure, presented higher validity and reliability values compared to the other tests.
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http://dx.doi.org/10.29390/001c.131842 | DOI Listing |
Front Physiol
February 2025
Institute of Human Movement Science, Sport and Health, University of Graz, Graz, Austria.
Introduction: There is a well-established relationship between the respiratory compensation point (RCP) and local muscular breakpoints determined from near-infrared spectroscopy (NIRS) and electromyography (EMG). However, these breakpoints have not yet been compared both in locomotor and non-locomotor muscles simultaneously in single-leg cycling exercise. Therefore, the aim of the study was to investigate the relationship and agreement between systemic and local breakpoints in locomotor and non-locomotor muscles.
View Article and Find Full Text PDFMuscle Nerve
March 2025
Department of Neurology, Virginia Commonwealth University, Richmond, Virginia, USA.
Introduction/aims: Studies examining racial differences in ALS have previously focused on diagnostic delay and disease severity. Time to critical clinical events has rarely been investigated, despite its importance in revealing differences in ALS patients' disease courses. This study explores racial disparities in time to specific clinical events in Black and non-Hispanic White ALS patients at a single center.
View Article and Find Full Text PDFJ Intensive Care
March 2025
Department of Anaesthesiology and Critical Care, AIIMS, Jodhpur, India.
We commend the authors for their insightful study on inspiratory muscle training (IMT) in mechanically ventilated patients with difficult weaning, highlighting the robust use of maximum inspiratory pressure (MIP) as a key outcome. We suggest that a lower baseline maximum inspiratory pressure cutoff could better target patients with significant inspiratory dysfunction, improving the study's precision. Additionally, alternative imputation techniques, such as multiple imputation, could strengthen the handling of missing data.
View Article and Find Full Text PDFParasit Vectors
March 2025
Nature Research Centre, Akademijos 2, 08412, Vilnius, Lithuania.
Background: The cyst-forming coccidia of the genus Sarcocystis (Sarcocystidae) are widespread protists of mammals, particularly of domestic and wild ruminants. Research on genus Sarcocystis in wild members of the subfamily Caprinae is, however, rather limited. Sarcocystis in the Alpine ibex (Capra ibex) have only been investigated in depth once and then solely by morphological techniques.
View Article and Find Full Text PDFCell Signal
March 2025
Department of Pulmonary and Critical Care Medicine, Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Department of Clinical Laboratory Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Peking Union Medical College; Beijing, China. Electronic address:
Objective: Pulmonary arterial hypertension (PAH) is a serious consequence of congenital heart disease (CHD). PAH is characterized by a cancer-like pro-proliferative and anti-apoptotic phenotype of pulmonary artery smooth muscle cells (PASMCs). Never in mitosis a-related kinase 2 (NEK2) has recently been identified as a key factor in tumor cell proliferation and migration whlie the functional importance of NEK2 in PAH associated with CHD (CHD-PAH) has not been elucidated yet.
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