Hyperparathyroidism with urinary calculus as the initial symptom is common; however, carcinomas of the parathyroid gland are rare. Moreover, synchronous cancers have rarely been reported. A man in his 50s presented to our hospital with a 1-month history of left lumbar back pain. After close examination, urinary calculus, parathyroid carcinoma, and lung cancer were detected. He underwent surgical treatment followed by additional anticancer drugs. Two and a half years following his first visit to our hospital, no recurrence has been observed. Parathyroid carcinoma should be considered as a cause of urinary calculus, and synchronous cancers, including rare cancer, can also exist.
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http://dx.doi.org/10.1093/jscr/rjaf121 | DOI Listing |
EFORT Open Rev
February 2025
Alkaptonuria is an extremely rare disorder of tyrosine metabolism caused by an autosomal recessive enzymatic deficiency of homogentisic acid (HGA) oxidase, causing its accumulation in collagenous structures, especially in hyaline cartilage. It is characterized by a triad of homogentisic aciduria, bluish-black discoloration of connective tissues (ochronosis) and arthropathy of the spine and large weight-bearing joints. Several clinical manifestations were described including coronary and valvular calcification, aortic stenosis, limited chest expansion, and renal, urethral and prostate calculi as well as ocular and cutaneous pigmentation.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
March 2025
Department of Urology, Shengli Oilfield Central Hospital, Dongying, Shandong, China.
Background: Kidney stones are a chronic metabolic disorder. The cardiometabolic index (CMI) is a new and easily accessible measure used to assess metabolic status. However, the relationship between CMI and the incidence of kidney stones remains unclear.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Urology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
To identify independent risk factors for urosepsis in diabetic patients with upper urinary tract stones (UUTS) and develop a prediction model to facilitate early detection and diagnosis, we retrospectively reviewed medical records of patients admitted between January 2020 and June 2023. Patients were divided based on the quick Sequential Organ Failure Assessment (qSOFA) score. The least absolute shrinkage and selection operator (LASSO) regression analysis was used for variable selection to form a preliminary model.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Urology, Faculty of Medicine, Cukurova University, 01330, Adana, Turkey.
PCNL, a minimally invasive surgical technique for kidney stone removal, relies on achieving stone-free status, which various scoring systems aim to predict. This study assesses the predictive accuracy of the Clinical Research Office of the Endourological Society (CROES) and Guy's Stone Score (GSS) systems in determining stone-free rates following percutaneous nephrolithotomy (PCNL) in pediatric patients. A retrospective analysis was conducted on 580 pediatric patients who underwent PCNL at Çukurova University Urology Clinic between January 2007 and March 2024.
View Article and Find Full Text PDFUrolithiasis
March 2025
College of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, 030801, China.
Kidney stones are a common urological disease. Although there are many ways to treat them, their high recurrence rate remains unresolved. Research has demonstrated that Lysimachia christinae Hance influences kidney stone development; however, the exact mechanism remains unclear.
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