Acute Pericarditis Associated With Graves' Disease: A Case Report.

Cureus

Internal Medicine, Unidade Local de Saúde Gaia Espinho, Vila Nova de Gaia, PRT.

Published: February 2025

Acute pericarditis is an uncommon but significant complication of Graves' disease. This case report describes a 53-year-old female presenting with acute pericarditis in the context of newly diagnosed Graves' disease. The patient's clinical presentation, diagnostic evaluation, treatment course, and outcome are discussed. We also provide a comprehensive review of the literature on pericarditis associated with Graves' disease, including its pathophysiology, clinical features, diagnostic challenges, and therapeutic approaches. This report highlights the importance of considering thyroid dysfunction in cases of idiopathic pericarditis, as prompt diagnosis and targeted treatment can significantly improve outcomes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888993PMC
http://dx.doi.org/10.7759/cureus.78588DOI Listing

Publication Analysis

Top Keywords

graves' disease
16
acute pericarditis
12
pericarditis associated
8
associated graves'
8
disease case
8
case report
8
graves'
4
disease
4
report acute
4
pericarditis
4

Similar Publications

The thyroid is essential for the metabolic processes in the body, and its imbalance can cause acute and chronic health issues. Autoimmune thyroid disease includes both Hashimoto's thyroiditis (HT) and Graves' disease (GD). HT is the most common cause of hypothyroidism, while GD is the most common cause of hyperthyroidism.

View Article and Find Full Text PDF

Introduction: Proven risk factors for thyroid orbitopathy (TO) are thyroid dysfunction, smoking, and high levels of thyrotropin receptor antibodies (TRAb), and the role of insulin-like growth factor 1 (IGF-1), the receptor for IGF-1 (IGF-1R), and antibodies to the receptor for IGF-1 (IGF-1RAb) are also debated. IGF-1R is overexpressed in fibroblasts and orbital lymphocytes in TO patients. It forms a functional complex and mediates signal transduction through thyroid stimulating hormone receptor (TSHR).

View Article and Find Full Text PDF

It is widely recognized that one autoimmune disorder is sometimes associated with an increased frequency of having another autoimmune condition. However, the simultaneous presentation of Ulcerative colitis and Graves' disease is an underreported occurrence in the medical literature. We present the case of a previously healthy 36-year-old female who presented with acute symptoms of ulcerative colitis and Graves' disease simultaneously, leading to the diagnosis of both conditions within a short time frame.

View Article and Find Full Text PDF

Autoimmune diseases are a class of diseases wherein the immune system of the body targets itself through autoreactive T cells and autoantibodies. Autoimmune diseases are classified as organ-specific autoimmune diseases and systemic autoimmune diseases. Organ-specific autoimmune diseases such as primary biliary cirrhosis, Hashimoto's Thyroiditis (HT), Type 1 Diabetes mellitus (T1D), and Graves' Disease (GD) are characterized by a unique immune system response to autoantigens in a single organ.

View Article and Find Full Text PDF

Purpose: Thyroid eye disease (TED) presents challenges in the accurate assessment of disease activity, especially concerning ocular surface manifestations. This study aims to evaluate the potential of anterior segment optical coherence tomography angiography (AS-OCTA) in quantifying vascular changes associated with TED, thereby enhancing understanding of its pathophysiology and aiding in diagnosis and management.

Methods: We conducted a cross-sectional study involving 29 TED patients and 21 healthy controls.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!