Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11887938 | PMC |
http://dx.doi.org/10.7759/cureus.78556 | DOI Listing |
Cureus
February 2025
Pathology, Tzafon Medical Center, Azrieli Faculty of Medicine, Bar Ilan University, Tiberias, ISR.
Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.
View Article and Find Full Text PDFCureus
September 2024
Orthodontics and Dentofacial Orthopaedics, Army College of Dental Sciences, Secunderabad, IND.
A dentinogenic ghost cell tumor (DGCT) is a rare and locally aggressive benign mixed odontogenic tumor, histologically made up of ameloblast-like epithelial islands, ghost cells, and dentin-like material. This is a highly unusual example of DGCT combined with an odontoma in a 13-year-old female patient affecting the right maxilla. On radiographic examination, ill-defined radiolucency with right maxillary sinus obliteration and involvement of permanent maxillary right first and second molars were noted.
View Article and Find Full Text PDFHead Neck Pathol
October 2024
Surgical Pathology Laboratory, Oral Pathology Department, Facultad de Odontología, Universidad de Buenos Aires, M.T. Alvear 2142. (C1122AAH), Ciudad Autónoma de Buenos Aires, Argentina.
Autops Case Rep
August 2024
Department of Oral Medicine and Radiology, Post Graduate Institute of Dental Sciences, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India.
Dentinogenic ghost cell tumor (DGCT) is a rare benign neoplasm form of calcifying odontogenic cyst (COC) characterized by ghost cells. Although benign, it presents an aggressive behavior. DGCT accounts for 2% to 14% of all COCs and less than 0.
View Article and Find Full Text PDFOral Radiol
October 2024
Department of Oral and Maxillofacial Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558, Japan.
A dentinogenic ghost cell tumor (DGCT) is a rare benign odontogenic tumor that commonly shows characteristics of solid proliferation and has a relatively high risk of recurrence after surgical treatment. We herein report a case of a central DGCT that occurred in the maxilla and resulted in bone expansion. This study highlights new imaging findings (particularly magnetic resonance imaging) along with histopathological observations.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!