Central Dentinogenic Ghost Cell Tumor: A Rare Entity.

Cureus

Pathology, Tzafon Medical Center, Azrieli Faculty of Medicine, Bar Ilan University, Tiberias, ISR.

Published: February 2025

Odontogenic tumors are rare lesions with varied clinical presentations and behaviors. A dentinogenic ghost cell tumor (DGCT) is a rare odontogenic neoplasm that can be classified into central (intraosseous) and peripheral (extraosseous) types, with a central DGCT often presenting as a bone-expanding lesion. We report a case of a multimorbid 66-year-old male patient with a central DGCT presenting as a painless, 3 × 5.3 cm expansile mass in the right mandibular body. The patient underwent radiographic and histologic assessment followed by tumor enucleation under local anesthesia, which revealed classic features of the DGCT, including ghost cells, calcifications, and a low proliferation index, consistent with low malignant potential.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11887938PMC
http://dx.doi.org/10.7759/cureus.78556DOI Listing

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