Ballantyne syndrome is a rare obstetric condition characterized by fetal hydrops, maternal edema, and placentomegaly. Its low incidence, combined with potential clinical overlap with preeclampsia, poses significant diagnostic and management challenges. This condition is especially relevant due to the severe complications it can cause during pregnancy. In this article, we present a case of Ballantyne syndrome associated with Down syndrome (DS) and chorioamnionitis, complemented by a literature review exploring its possible etiologies, pathophysiology, and therapeutic options. Additionally, the importance of early diagnosis, the use of invasive techniques to identify underlying etiologies, and therapeutic decision-making focused on safeguarding maternal life are emphasized, including pregnancy termination in cases of severe complications to optimize maternal and fetal outcomes.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888777 | PMC |
| http://dx.doi.org/10.7759/cureus.78563 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Familial chylomicronemia syndrome and treatments to target hepatic APOC3 mRNA.
Atherosclerosis
January 2025
Division of Endocrinology and Metabolism, Department of Medicine, M0682, University of California San Diego, 9500 Gilman Dr, La Jolla, CA, USA. Electronic address:
Familial chylomicronemia syndrome (FCS) is a rare, recessive monogenic disorder characterized by severely elevated plasma triglyceride (TG) levels due to absent or markedly impaired lipoprotein lipase activity, leading to a greatly increased risk of acute pancreatitis. Naturally occurring very low levels of apoC-III are associated with low TG levels; thus, apoC-III is a target for TG lowering, and therapies have been developed to reduce apoC-III. Strategies to inhibit hepatic apoC-III synthesis include antisense oligonucleotides (ASOs) and small interfering RNAs (siRNAs).
View Article and Find Full Text PDFBallantyne Syndrome Related to Down Syndrome and Chorioamnionitis: A Case Report and Literature Review.
Cureus
February 2025
Obstetrics and Gynecology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, PER.
Ballantyne syndrome is a rare obstetric condition characterized by fetal hydrops, maternal edema, and placentomegaly. Its low incidence, combined with potential clinical overlap with preeclampsia, poses significant diagnostic and management challenges. This condition is especially relevant due to the severe complications it can cause during pregnancy.
View Article and Find Full Text PDFAn overview of persistent chylomicronemia: much more than meets the eye.
Curr Opin Endocrinol Diabetes Obes
April 2025
Université de Montréal, Department of Medicine, Montreal.
Purpose Of Review: The aim of this review is to provide an overview of severe hypertriglyceridemia presenting in the form of chylomicronemia that persists despite treatment of secondary causes and the use of conventional lipid-lowering treatment.
Recent Findings: Persistent chylomicronemia is a rare syndromic disorder that affects carriers of bi-allelic combinations of pathogenic gene variants impairing lipoprotein lipase (LPL) activity, as well as a significant number of individuals who do not meet this genetic criterion. It is associated with a high risk of acute pancreatitis and other morbidities.
Adipokines and Transitions in Metabolic Health Over Time: The Atherosclerosis Risk In Communities (ARIC) Study.
J Clin Endocrinol Metab
January 2025
Division of Cardiology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Context: Transitions in metabolic health status over time are strongly linked to risk for cardiovascular events, particularly among individuals with obesity. Adipokines are proteins with metabolic effects, but their role in transitions in metabolic health status over time is unknown.
Objective: To evaluate the associations of adiponectin and leptin with metabolic risk transitions over time.
Freshwater Mussel (Unio pictorum) Shells Reveal Hydrological and Environmental Change From 1300 BC to the Present Day.
Glob Chang Biol
October 2024
Department of Zoology, David Attenborough Building, University of Cambridge, Cambridge, UK.
Preserved biological communities can provide baseline data about the historical ecosystems and environmental conditions that preceded recent anthropogenic alteration. Freshwater mussel shells show particularly good preservation, and the shell assemblages commonly found during archaeological excavations can offer insights into past ecosystems. We studied assemblages of Unio pictorum mussel shells from palaeochannel silts associated with the Late Bronze Age site of Must Farm in eastern England (c.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!