Background: Antimicrobial resistance (AMR) is an increasing worldwide health concern, and non-adherence to antibiotic medication is a crucial factor in its growth. The objective of this research was to assess the adherence of dental patients in Saudi Arabia to oral antibiotic therapy, their knowledge of AMR, and their precise antibiotic prescription.
Methodology: From February 2023 to July 2023, a descriptive quantitative study was conducted among 450 outpatient dental patients who had obtained antibiotic prescriptions from dentists in the previous year. The questionnaire included three elements: knowledge of AMR, antibiotic usage behavior, and demographic information.
Results: During the study, it was found that only 3.6% of participants showed complete adherence to antibiotic therapy; 34% showed adherence to antibiotic therapy to a moderate extent, while 62.3% exhibited low adherence. Statistically significant relationships were established between age and income, and patients' adherence levels, with considerably lower adherence among the younger and the patients with lower income. Despite 72.5% admitting the importance of appropriate use of antibiotics, 68.8% said they had stopped taking the antibiotic medication once they started to feel better, and 35.3% used lower prescribed doses.
Conclusion: The results of the study suggest that the level of adherence to antibiotic prescription among dental patients in Saudi Arabia is low, and this is of great concern to AMR. It is hereby imperative to tackle the elements that lead to nonadherence to maintain the efficacy of antibiotics and protect public health. Healthcare stakeholders can achieve AMR reduction and optimal patient outcomes by implementing focused interventions and public health efforts.
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http://dx.doi.org/10.7759/cureus.78599 | DOI Listing |
Eur J Clin Microbiol Infect Dis
March 2025
Independant Microbiology Advisor, Jan Van Goyenplein 31, 2231 MM, Rijnsburg, The Netherlands.
Purpose: Urinary Tract InfectionAQ1 (UTI) affects over 400 million people annually and globally and is a major reason for empiric antibiotic prescription by general practitioners (GPs).
Background: A problem related to microbiological UTI diagnosis is the current lack of point of care (POC) diagnostics. In addition, remote settings, including low and middle income countries (LMIC), are hard to service.
Cureus
February 2025
Department of Pharmacy, Saint Francis Health System, Tulsa, USA.
Background: Open fracture wounds are associated with a high risk of infection, though the outcomes are dependent on the fracture location, prophylactic antibiotics utilized, and time to antibiotic intervention. Although several institutions have provided guidelines for appropriate prophylaxis in open fractures, there is currently no consensus on antibiotic selection and duration. Reducing inappropriate prophylactic antibiotic use for open bone fractures is a potential stewardship opportunity within pharmacy departments.
View Article and Find Full Text PDFCureus
February 2025
Department of Prosthodontics, College of Dentistry, Qassim University, Buraydah, SAU.
Background: Antimicrobial resistance (AMR) is an increasing worldwide health concern, and non-adherence to antibiotic medication is a crucial factor in its growth. The objective of this research was to assess the adherence of dental patients in Saudi Arabia to oral antibiotic therapy, their knowledge of AMR, and their precise antibiotic prescription.
Methodology: From February 2023 to July 2023, a descriptive quantitative study was conducted among 450 outpatient dental patients who had obtained antibiotic prescriptions from dentists in the previous year.
J Nanobiotechnology
March 2025
State Key Laboratory of Agricultural and Forestry Biosecurity & Key Lab of Biopesticide and Chemical Biology, Ministry of Education & Ministerial and Provincial Joint Innovation Centre for Safety Production of Cross-Strait Crops, College of Plant Protection, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, P. R. China.
Background: Environmentally responsive nanoscale biocide delivery system enhances smart, regulated, and synergistic biocide application with precise biocide release. In this study, pectin-modified dendritic mesoporous silica nanoparticles (DMSNs) was used as a carrier to successfully construct a microenvironment-responsive (pH, temperature and enzyme) eugenol nano-biocide delivery system for the control of Ralstonia solanacearum infection.
Results: The results showed that the specific surface area, pore size and surface activity of DMSNs significantly influence the biocide loading of eugenol, and the biocide loading capability was up to 72.
BMC Musculoskelet Disord
March 2025
Department of Orthopedic Surgery, College of Medicine, Riyadh, Saudi Arabia.
Background: Coccygectomy is the definitive treatment of coccygodynia refractory to conservative therapy, but post operative wound infection poses a significant challenge in these patients. We introduce a novel peri-operative technique incorporating a specific pre-operatively dietary regimen, polyethylene glycol enema, and prophylactic antibiotics. Post-operatively, patients adhered to strict hygienic protocols in addition to receiving antibiotics.
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