Currently, standard protocols for body imaging and corresponding image processing pipelines in population-based cohort studies are unavailable, limiting the applications of body imaging. Based on the China Phenobank Project (CHPP), the present study described a body imaging protocol for multiple organs, including cardiac structures, liver, spleen, pancreas, kidneys, lung, prostate, and uterus, and the corresponding image processing pipelines promoted its development. Briefly, the body imaging protocol comprised a 40-min cardiac magnetic resonance imaging (MRI) scan, a 5-min computed tomography (CT) scan, a 20-min abdominal MRI scan, and a 10-min pelvic MRI scan. The recommended image processing pipeline utilized deep learning segmentation models to facilitate the analysis of large amount of data. This study aimed to provide a reference for planning studies based on the CHPP platform.
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http://dx.doi.org/10.1007/s43657-023-00141-x | DOI Listing |
Echocardiography
March 2025
Department of Physical Therapy, Faculty of Health Science, Kyorin University, Mitaka City, Tokyo, Japan.
Purpose: Central hypovolemia is considered to lead to a compensatory increase in cardiac contractility. From a physiological perspective, left ventricular (LV) twisting motion, which plays an important role in maintaining cardiac output, should be enhanced during central hypovolemia, but previous studies have shown inconsistent findings. Using 3D echocardiography, we tested the hypothesis that the LV twisting and untwisting motion would be enhanced during severe central hypovolemia.
View Article and Find Full Text PDFSci Adv
March 2025
Department of Mechanical and Automation Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.
Recalcitrant biofilm infections pose a great challenge to human health. Micro- and nanorobots have been used to eliminate biofilm infections in hard-to-reach regions inside the body. However, applying antibiofilm robots under physiological conditions is limited by the conflicting demands of accessibility and driving force.
View Article and Find Full Text PDFSci Adv
March 2025
Department of Neurology, Johns Hopkins University, Baltimore, MD 21205, USA.
There is great interest in using genetically tractable organisms such as to gain insights into the regulation and function of sleep. However, sleep phenotyping in has largely relied on simple measures of locomotor inactivity. Here, we present FlyVISTA, a machine learning platform to perform deep phenotyping of sleep in flies.
View Article and Find Full Text PDFJ Immunol
February 2025
Immunology and Microbiology Department, Dasman Diabetes Institute, Dasman, Kuwait.
The relationship between sleep deprivation, obesity, and systemic inflammation is a critical area of investigation due to its significant impact on health. While it is established that poor sleep adversely affects obesity and metabolic syndromes, the specific mechanisms, particularly subclinical inflammation independent of obesity, remain unclear. This study investigates how sleep quality influences monocyte subclass distribution and its association with systemic inflammation across a spectrum of body mass index categories.
View Article and Find Full Text PDFRev Bras Enferm
March 2025
Universidade Federal de São Paulo. São Paulo, São Paulo, Brazil.
Objectives: to evaluate the quality of life and body image in women with breast cancer during chemotherapy, before and after interventions targeting body image.
Methods: we conducted a prospective cohort study with 47 women, utilizing both qualitative and quantitative data analysis.
Results: in the semi-structured interviews, 52.
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