Osteosarcoma is a rare malignant tumor that primarily affects the jaw bones, with the low-grade chondroid variant being an uncommon subtype that often mimics benign lesions. This case report details the clinical presentation, histopathological findings, radiographic evidence, and treatment approach for a 23-year-old male who presented with recurrent gingival growth and pain in the lower anterior region. Initially misdiagnosed as a pyogenic granuloma, further evaluation revealed the presence of low-grade chondroid variant osteosarcoma. This case underscores the necessity for a thorough investigation of recurrent oral lesions and the importance of timely biopsy and accurate histopathological interpretation for effective management. The unique radiographic and histopathological features of this variant are discussed, emphasizing the critical need for differential diagnosis in similar clinical scenarios.
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http://dx.doi.org/10.4103/jpbs.jpbs_1292_24 | DOI Listing |
J Pharm Bioallied Sci
December 2024
Department of Oral Pathology and Microbiology, Sree Balaji Dental College and Hospitals (SBDCH), Oral Cancer Prevention Awareness and Research (COCPAR), Bharath University (BIHER), Chennai, Tamil Nadu, India.
Osteosarcoma is a rare malignant tumor that primarily affects the jaw bones, with the low-grade chondroid variant being an uncommon subtype that often mimics benign lesions. This case report details the clinical presentation, histopathological findings, radiographic evidence, and treatment approach for a 23-year-old male who presented with recurrent gingival growth and pain in the lower anterior region. Initially misdiagnosed as a pyogenic granuloma, further evaluation revealed the presence of low-grade chondroid variant osteosarcoma.
View Article and Find Full Text PDFSkeletal Radiol
March 2025
Department of Radiology, Allegheny Health Network, 320 E North Ave, Pittsburgh, PA, 15212, USA.
Background: Central cartilage tumors are common incidental lesions around knee and shoulder joints. Differentiation of low-grade chondroid lesions, such as enchondroma from atypical cartilaginous tumor (ACT) is often difficult on imaging given pathologic and radiologic similarities. The Birmingham atypical cartilage tumor imaging protocol (BACTIP) provides a guide to initial assessment and imaging follow-up for incidental indeterminate central cartilage tumors.
View Article and Find Full Text PDFAtypical cartilaginous tumor (ACT) refers to a low-grade cartilaginous neoplasm microscopically identical to grade 1 chondrosarcoma, affecting the appendicular skeleton. Treatment with intralesional curettage has been found to provide sufficient local control with less morbidity compared to wide resection. This is the first reported case of a simultaneous medial patello-femoral ligament (MPFL) reconstruction with extended curettage for ACT on the ipsilateral femur.
View Article and Find Full Text PDFAm J Clin Pathol
May 2024
Department of Pathology and Theranostics, Institut Curie, Paris, France.
Objectives: Cytology reports of metaplastic breast carcinoma (MBC) are rare and limited to short series and simple case reports. To adapt cytology diagnostic criteria to the most recent fifth edition of the World Health Organization Classification of Breast Tumours from 2019, we have reviewed our series from the files of the Institut Curie.
Methods: A cohort of 66 female patients investigated by cytology with corresponding histologic diagnosis of MBC was identified.
Front Oncol
August 2023
Department of Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.
Introduction: Enchondromas and grade 1 chondrosarcomas are commonly encountered low-grade chondroid tumors in the proximal humerus. While there is a concern for malignant transformation, few studies have evaluated the natural history of these lesions. The purpose of this study is to evaluate the natural history of proximal humerus low-grade chondroid lesions managed both conservatively and surgically, and to define management criteria using clinical and radiographic findings for these low-grade chondroid lesions.
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