Introduction: Owing to limitations of various flap procedures for the management of oral submucous fibrosis (OSMF), we tried to evaluate the outcome of the buccal fat pad (BFP) with collagen membrane as an alternative.
Materials And Methods: We performed the aforementioned technique on eight patients diagnosed with OSF who underwent management using the BFP with a collagen membrane.
Results: We observed a significant mean gain in mouth opening of 5.29 ± 2.11 mm and a significant reduction in pain levels by 2.62 ± 1.05. No complication and recurrence were observed till fourmonth followup.
Conclusion: It can be concluded that the BFP with a collagen membrane could be a viable alternative to other surgical procedures. However, our data should extrapolate with larger studies with longer followup.
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http://dx.doi.org/10.4103/jpbs.jpbs_1335_24 | DOI Listing |
Nanomaterials (Basel)
March 2025
Department of Materials Science and Engineering, University of Crete, 700 13 Heraklion, Greece.
Chronic or improperly healed wounds, either as a result of extended trauma or prolonged inflammatory response, affect a significant percentage of the world population. Hence, there is a growing interest in the development of biomimetic scaffolds that expedite wound closure at the early stages. Curcumin (Cur) is a plant-derived polyphenol with antimicrobial activity, and it accelerates the wound contraction rate.
View Article and Find Full Text PDFJ Appl Biomater Funct Mater
March 2025
Kerman Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Peripheral nerve tissue engineering is a field that uses cells, growth factors and biological scaffold material to provide a nutritional and physical support in the repair of nerve injuries. The specific properties of injectable human amniotic membrane-derived hydrogel including growth factors as well as anti-inflammatory and neuroprotective agents make it an ideal tool for nerve tissue repair, and metformin may also aid in nerve regeneration. The aim of this study was to investigate the effects of hydrogel derived from amniotic membrane (AM) along with metformin (MET) administration in the repair of sciatic nerve injury in male rats.
View Article and Find Full Text PDFCell Transplant
March 2025
Cardiovascular Research Unit, IRCCS MultiMedica, Milan, Italy.
Diabetic foot ulcers (DFUs) are associated with a high risk of amputations and a 50% 5-year survival rate due at least in part to the limited angiogenic and wound healing capacity of patients with diabetes. Cell therapy via intramuscular injection of peripheral blood mononuclear cells showed encouraging but limited results. Such limitations may arise from the limited ability of therapeutic cells to adhere to the target tissue.
View Article and Find Full Text PDFClin Implant Dent Relat Res
April 2025
Department of Advanced General Dentistry, Yonsei University College of Dentistry, Seoul, Korea.
Introduction: This study aimed to determine possible histological and radiological differences in alveolar ridge preservation (ARP), using moldable bone versus particulate bone.
Methods: After tooth extraction, 39 patients (40 teeth) were randomized (1:1) to receive ARP using moldable bone materials (SBX group) or particulate bone materials (PBX group). An absorbable collagen membrane was placed over the graft material and the surgical site was sutured.
Dev Cell
March 2025
Department of Translational Neurosciences, University of Arizona, College of Medicine, Phoenix, AZ 85004, USA.
The tectorial membrane extracellular matrix in the cochlea controls auditory transduction, but its earliest development remains unclear. In this issue of Developmental Cell, Niazi et al. have provided insight into tectorial membrane formation, demonstrating proteolytic shedding early in development and interaction with α-tectorin and collagen.
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