Artemisia annua L., also referred to as sweet wormwood, sweet annie, sweet sagewort, and annual wormwood (Chinese: qngho), is a species of wormwood native to temperate Asia but naturalised worldwide. It is a member of the Asteraceae family. At the moment, Artemisia annua is the sources of artemisinin and semisynthetic artemisinin derivatives (including dihydroartemisinin, artesunate, artemether, and arteether) used in the development of malaria combination treatments (ACTs = Artemisinin-based combination therapy). Animal experiments have shown that similar chemicals can prevent tumor development and metastasis. Furthermore, there is no conclusive proof from human trials that the benefits seen in animal research extend to cancer patients. Experiences with malaria treatment indicate that artemisinin-based medicines are generally well-tolerated. This study highlights A. annua's traditional use and contemporary pharmacological research, bringing unique insights into the usage of A. annua in the treating a wide range of ailments.
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http://dx.doi.org/10.4103/jpbs.jpbs_1250_24 | DOI Listing |
The green synthesis of metal nanoparticles has garnered significant attention due to its simplicity, cost-effectiveness, and environmental sustainability. Gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs) are widely employed across various industries, agriculture, and medicine owing to their unique physicochemical properties. This study explores the feasibility of synthesizing metal nanoparticles through green methods using ethanolic (70%) extracts from Artemisia annua hairy roots.
View Article and Find Full Text PDFJ Pharm Bioallied Sci
December 2024
Department of Paediatrics, Faculty of Medicine, Sri Lalithambigai Medical College and Hospital, Dr. M.G.R. Educational and Research Institute, Chennai, Tamil Nadu, India.
Artemisia annua L., also referred to as sweet wormwood, sweet annie, sweet sagewort, and annual wormwood (Chinese: qngho), is a species of wormwood native to temperate Asia but naturalised worldwide. It is a member of the Asteraceae family.
View Article and Find Full Text PDFCurr Drug Deliv
March 2025
School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong, 518055, China.
Background: Plant-derived extracellular vesicles (PDEVs) are vital for intercellular material exchange and information transfer. They significantly regulate cellular functions, tissue repair, and self-defense mechanisms.
Objective: This review summarizes the formation pathways, composition, and potential applications of PDEVs in anti-tumor research and drug delivery systems.
Virol Sin
March 2025
Department of Immunology, International Cancer Center, Shenzhen University Medical School, Shenzhen 518055, China. Electronic address:
Artemisia annua L. is a medicinal herb with multiple therapeutic applications, whereas its anti-influenza A virus (IAV) efficiency and mechanism of action are still unclear. Here, we investigated the inhibition activity and mechanism of A.
View Article and Find Full Text PDFHeliyon
February 2025
Department of Animal Biotechnology, College of Life Science, Sangji University, Wonju-si, 26339, Republic of Korea.
Artemisinin, a compound derived from , is primarily utilized for malaria treatment. Its mechanism of action involves the rapid and effective inhibition of protein synthesis in malarial parasites. Recently, artemisinin has garnered extensive research attention for its anticancer, antioxidant, and anti-inflammatory properties, as well as its potential role as an adjuvant in cancer treatment.
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