This case report describes a 45-year-old male who presented with mobility and dull pain in the lower right back tooth region for two months. Initially diagnosed with localized periodontitis at a private clinic, the patient sought a second opinion. Clinical examination revealed slight obliteration of the buccal vestibule and mobility in teeth 45 and 46. Radiographic findings showed a unilocular radiolucency in the periapical region of the premolar and first molar. This case highlights the importance of including granular cell ameloblastoma in the differential diagnosis of mandibular lesions and stresses the need for thorough clinical and radiographic evaluation to avoid misdiagnosis and ensure proper treatment.
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http://dx.doi.org/10.4103/jpbs.jpbs_1294_24 | DOI Listing |
Proteomics
March 2025
Department of Biotechnology, Delft University of Technology, Delft, the Netherlands.
Extracellular proteins are supposed to play crucial roles in the formation and structure of biofilms and aggregates. However, often little is known about these proteins, in particular for microbial communities. Here, we use two advanced metaproteomic approaches to study the extracellular proteome in a granular Candidatus Accumulibacter enrichment as a proxy for microbial communities that form solid microbial granules, such as those used in biological wastewater treatment.
View Article and Find Full Text PDFBrain Struct Funct
March 2025
The School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, 4072, Australia.
The Hippo signalling cascade is an evolutionarily conserved pathway critical for the development of numerous organ systems and is required for the development of many parts of the mammalian nervous system, including the cerebellum. The Hippo pathway converges, via the nuclear YAP/TAZ co-transcription factors, on transcription factors of the TEA Domain (TEAD) family (TEAD1-4) and promotes the expression of pro-proliferative genes. Despite the importance of TEAD function, our understanding of spatial and temporal expression of this family is limited, as is our understanding of which TEAD family members regulate Hippo-dependent organ development.
View Article and Find Full Text PDFTicks Tick Borne Dis
March 2025
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China. Electronic address:
Ticks (Haemaphysalis longicornis) transmit pathogens to their hosts through their salivary glands during blood-feeding. The salivary glands of adult parthenogenetic H. longicornis undergo degeneration post-engorgement.
View Article and Find Full Text PDFOncologist
March 2025
State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, 300020, People's Republic of China.
NK-large granular lymphocytic leukemia (NK-LGLL) is a rare chronic lymphoproliferative disorder and displays heterogeneity that remains insufficiently defined. CD56 plays a pivotal role in NK-cell maturation linked to cytotoxicity. However, whether CD56 might be associated with distinctive characteristics in NK-LGLL has not been determined.
View Article and Find Full Text PDFAnat Histol Embryol
March 2025
Department of Veterinary Anatomy, College of Veterinary Science, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India.
This study was conducted on 12 adult pigs of a local mixed breed to examine the histology, histochemistry and ultrastructure of the choroid and retinal pigmented epithelium (RPE). The tissues were fixed in Davidson's Fluid for light microscopy and Karnovsky's fluid for electron microscopy. Due to the physiological, anatomical and metabolic similarities between pigs and humans, pigs are a suitable animal model for various ophthalmic studies.
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