Introduction: The emergence of antibiotic-resistant pathogenic bacteria has become a major global health concern, with the increasing prevalence of infections that are difficult to treat with conventional antibiotics. As a result, there is a critical need for alternative antimicrobial agents that can effectively control bacterial infections and combat the growing problem of antibiotic resistance.
Materials And Methods: In this study, the antibacterial properties of lemon juice mediated zinc oxide nanoparticles (ZnO NPs) and titanium dioxide nanoparticles (TiO2 NPs) was evaluated against oral pathogens. The synthesized nanoparticles were characterized using UV-Vis spectroscopy. The antimicrobial activity of the nanoparticles was determined by the agar well diffusion assay.
Results: Our results showed that both ZnO NPs and TiO2 NPs exhibited potent antimicrobial activity against both and . Our findings suggest that the antimicrobial activity of ZnO NPs and TiO2 NPs is attributed to the disruption of bacterial cell membrane integrity and inhibition of bacterial growth.
Conclusion: Therefore, lemon juice mediated ZnO NPs and TiO2 NPs can be considered as promising antimicrobial agents for controlling bacterial infections.
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http://dx.doi.org/10.4103/jpbs.jpbs_854_24 | DOI Listing |
J Pharm Bioallied Sci
December 2024
Department of Pharmacology, Saveetha Dental College and Hospital, SIMATS, Saveetha University, Chennai, Tamil Nadu, India.
Introduction: The emergence of antibiotic-resistant pathogenic bacteria has become a major global health concern, with the increasing prevalence of infections that are difficult to treat with conventional antibiotics. As a result, there is a critical need for alternative antimicrobial agents that can effectively control bacterial infections and combat the growing problem of antibiotic resistance.
Materials And Methods: In this study, the antibacterial properties of lemon juice mediated zinc oxide nanoparticles (ZnO NPs) and titanium dioxide nanoparticles (TiO2 NPs) was evaluated against oral pathogens.
J Hazard Mater
February 2025
Department of Clinical Laboratory Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, China; Department of Pathogen Biology, School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China; Medical Science and Technology Innovation Center, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China. Electronic address:
The rising pollution from zinc oxide nanoparticles (ZnO-NPs) poses significant global concerns due to their widespread environmental presence and potential negative effects on human health. This study explores how ZnO-NPs impact migrasomes formation, a crucial process for cellular migration and communication. Our findings indicate that 28 nm ZnO-NPs enhance migrasomes formation, correlating with increased levels of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] and GTP-RhoA-essential molecules in migrasomes biogenesis.
View Article and Find Full Text PDFACS Appl Mater Interfaces
March 2025
Graduate School of Semiconductor Materials and Devices Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Republic of Korea.
Beyond the von Neumann architecture, neuromorphic computing attracts considerable attention as an energy-efficient computing system for data-centric applications. Among various synapse device candidates, a memtransistor with a three-terminal structure has been considered to be a promising one for artificial synapse with controllable weight update characteristics and strong immunity to disturbance due to decoupled write and read electrode. In this study, oxygen ion exchange-based electrochemical random-access memory consisting of the ZnO channel and CeO nanoparticle (NP) assembly as a gate insulator, also as an ion exchange layer, is proposed and investigated as an artificial synapse device for neuromorphic computing.
View Article and Find Full Text PDFInt J Biol Macromol
March 2025
College of Food Science, Northeast Agricultural University, Harbin, Heilongjiang 150030, PR China. Electronic address:
In this study, a composite film (CF) made of polyvinyl alcohol, pullulan, and ZnO nanoparticles was prepared by solution casting. The CF were applied to the postharvest preservation of Allium mongolicum Regel. Widely targeted metabolomics analysis of A.
View Article and Find Full Text PDFBiomater Adv
February 2025
Department of Chemistry and Centre for Nanomaterials and Devices, RV College of Engineering, Bangalore 560059, India. Electronic address:
The extreme survivability of infectious microorganisms on various surfaces prompts for the risk of disease transmissions, posing a perilous concern for global health. Thus, the treatment of these pathogenic microorganisms using the nanomaterials functionalized with antimicrobial coatings reaps relevant scope in the ongoing trend of research. Driven by their admirable biocompatibility, cost-effectiveness, and minimal toxicity, ZnO nanoparticles (ZnO-NPs) based antimicrobial hybrid coatings have emerged as a robust material to prevent the growth of infectious microorganisms on various surfaces, which in turn boosted their applications in the area of biomedical sciences.
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