Background: Aesthetic procedures for penile enhancement, such as the Penuma silicone sleeve implant, have gained increasing attention for addressing concerns like perceived size, buried or retractile penis, and mild curvature.
Aim: To assess the online search interest over time for penile enhancement modalities, analyze the trends, and explore any regional disparities in search patterns.
Methods: Google Trends data from June 18, 2018, to June 11, 2023, were utilized to analyze search interest for Penuma, penile implant, penile girth, Hyaluronic acid (HLA) injection, and penis injection. The results were compared to the trend data for Penuma from 2004 to 2023. Trendlines were generated to assess the changes in search interest over time and determine if they followed a random or polynomial trend. The highest search interest locations were identified for each term, and the corresponding regional gross domestic product values were collected.
Outcomes: Search interest was assessed in terms of volume, temporal trends, and regional disparities.
Clinical Implications: Understanding regional and temporal search patterns for penile enhancement can guide healthcare professionals and policymakers in developing targeted educational initiatives and allocating resources to meet patient needs.
Strengths And Limitations: The use of Google Trends provides a comprehensive and real-time assessment of public interest over a broad timeframe and geographic range. However, search interest data may not fully capture actual patient behaviors or clinical demand, and the analysis relies on assumptions about search terms accurately reflecting consumer intent.
Results: Penuma initially garnered interest upon its introduction in 2004 but experienced a decline until around March 2021. Comparing Penuma with other terms, general searches for penile implant and penile girth exhibited significantly higher interest than Penuma. The trendlines indicated increasing search interest for penile implant and HLA injection, while Penuma demonstrated a declining trend. In terms of regional disparities, the highest search interest for Penuma was observed in San Antonio, TX, while penile girth searches were highest in Oklahoma City, OK. Penile implant searches were prominent in Mobile, AL, and Birmingham, AL. Notably, HLA injection searches peaked in New York, NY, and penis injection searches were most prevalent in Los Angeles, CA.
Conclusion: This study reveals that online interest in Penuma lags other penile enhancement terms, with notable regional disparities in search patterns. These findings underscore the need for further research to understand the factors influencing these trends and to help healthcare professionals tailor educational efforts and resources to diverse consumer needs.
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http://dx.doi.org/10.1093/sexmed/qfaf013 | DOI Listing |
Disabil Health J
March 2025
School of Psychology, The University of Adelaide, SA, 5000, Australia.
Background: The importance of health literacy in personal health management is widely recognised in the general population, yet remains poorly understood in some patient groups, including people with spinal cord injury or disorder (SCI/D).
Objectives: The systematic review had two objectives: (1) to determine the health literacy levels of individuals with SCI/D, and (2) to identify facilitators and barriers to developing health literacy in this group.
Methods: Seven databases (CINAHL, Embase, Emcare, ProQuest, PsycINFO, PubMed, and Web of Science) were searched from inception, with an updated search completed on January 21, 2025.
Br J Anaesth
March 2025
Department of Surgical Interventional Sciences, McGill University Health Center, Montreal, QC, Canada; Department of Anesthesia, McGill University, Montreal, QC, Canada; Department of Surgery, McGill University, Montreal, QC, Canada. Electronic address:
Background: In the UK, total intravenous anaesthesia (TIVA) is used in 25% of general anaesthetics and is gaining traction because of its lower environmental impact and effectiveness in reducing postoperative nausea and vomiting (PONV). Although meta-analyses have compared TIVA and inhalational anaesthesia (IA), the optimal delivery method-manual infusion or target-controlled infusion (TCI)-remains underexplored. This review addresses this gap, leveraging the rapidly growing body of evidence to guide optimal anaesthetic practice.
View Article and Find Full Text PDFAcad Radiol
March 2025
Department of Nuclear Medicine, Beijing Luhe Hospital, Capital Medical University, Xinhua Road 82, Tong Zhou District, 101199 Beijing, China.
Rationale And Objectives: The objective of this research is to carry out a systematic review and meta-analysis to detect the diagnostic efficacy of 68Ga-FAPI Positron Emission Tomography (PET) Computed Tomography/Magnetic Resonance (CT/MR) in total of the lesions as well as different aspects of metastasis in individuals with ovarian cancers (OC).
Materials And Methods: The PubMed, Embase, Cochrane library, and Web of Science databases were thoroughly searched until the cut-off date of July 23, 2024. The assessment of 68Ga-FAPI PET CT/MR of OC was presented by the included studies.
Bull Cancer
March 2025
Pediatric Oncology, insitut Gustave-Roussy, Villejuif, France. Electronic address:
Amongst Ewing sarcoma family of tumours, (EFST), cutaneous/subcutaneous Ewing sarcoma are defined as tumours arising from cutaneous or subcutaneous tissue, not invading the underlying aponeurosis. They are rare tumours, with less than 200 patients published. They are typically small tumours (less than 5cm), and can arise at any anatomical location, with a particular tropism for distal, truncal and head/neck locations, compared to classical Ewing sarcoma.
View Article and Find Full Text PDFACS Nano
March 2025
Center for Nanomedicine, Institute for Basic Science (IBS), Seoul 03722, Korea.
Electron beams evolved as important tools for modern technologies that construct and analyze nanoscale architectures. While electron-matter interactions at atomic and macro scales are well-studied, a knowledge gap persists at the molecular to nano level─the scale most relevant to the latest technologies. Here, we employ liquid-phase transmission electron microscopy supported by density functional theory calculations and a mathematical random search algorithm to rationalize and quantify electron beam-induced processes at the molecular level.
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