Large left atrial myxoma with synchronous laryngeal squamous cell carcinoma: A case report.

Background: Cardiac myxoma is a benign neoplasm and one of the most common types of primary cardiac tumors. Synchronous cardiac myxoma and other malignancies are extremely rare, and only limited cases have been reported.

Case Summary: We describe a young patient with newly diagnosed locally advanced laryngeal cancer, with a synchronous cardiac tumor detected on staging scans. An echocardiogram showed the typical appearance of myxoma in the left atrium. Early cardiac surgery was performed in view of its obstructive features and post cardiac surgery recovery was uneventful. The patient was scheduled for subsequent oncological treatment for the laryngeal cancer. However, due to rapid progression of the advanced laryngeal malignancy, he was placed on supportive care.

Conclusion: To our knowledge, this is the first reported case of synchronous cardiac myxoma with laryngeal malignancy. Individualized treatment strategy should be adopted to manage synchronous tumors in a multidisciplinary approach. The most life-threatening condition needs be treated first. Single resection, staged operations or simultaneous resection of both tumors have been reported with good outcomes.