Background: Non-drug therapy is a common clinical treatment for chronic insomnia, and the effect of happiness perception training group based on five senses therapy on chronic insomnia has not been evaluated.
Objective: This study investigated the effects of happy sensation training group on anxiety, depression and insomnia symptoms in patients with chronic insomnia disorder.
Methods: A prospective, assessor-blind, randomized controlled design was used. Adult patients with chronic insomnia were recruited from the Sleep Medicine Center of Sichuan Provincial Center for Mental Health. Participants in the training group received 10 sessions of hospital-based happy sensation training group therapy and three months of home exercises. The control group received health instruction. Results included anxiety, depression, and insomnia and were assessed at baseline, 2-week intervention, and 3-month follow-up. Polysomnography was performed at baseline and 2-week intervention. Two-way repeated measure ANOVA and Nonparametric test were used for data analysis.
Results: 42 patients in the training group and 43 patients in the control group accomplished 3-month follow-up. There was no significant difference in anxiety, depression, insomnia and sleep Characteristics between training group and control group at baseline ( > 0.05). Compared with the control group, anxiety, depression and insomnia were improved in the training group after 2 weeks and at the 3-month follow-up ( < 0.05), sleep latency was shortened ( < 0.001), and sleep efficiency, total sleep time and N2 phase sleep were increased ( < 0.05).
Conclusion: Happiness sensation training group can effectively improve the anxiety and depression of chronic insomnia patients, so as to improve insomnia. Given its acceptability and practicality, the program could be incorporated into routine treatment.
Clinical Trial Registration: https://www.chictr.org.cn/bin/project/edit?pid=210919, identifier ChiCTR2400082199.
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http://dx.doi.org/10.3389/fnins.2025.1414143 | DOI Listing |
Org Lett
March 2025
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Mohali 160062, India.
A one-pot process involving cycloaddition of the azaoxyallyl cation with thioamide and a synchronous E1-type elimination of the C2 amino group from the cycloadduct is disclosed, leading to diverse alkylidene-4-thiazolidinones. Amine elimination under acid-free conditions or without quaternization and forging a stereoselective olefin formation were among the interesting reactivity traits revealed through the present work. Conjugated thioamide permitted side-chain branching through a three-component process.
View Article and Find Full Text PDFRev Environ Health
March 2025
Key Laboratory of Environment Remediation and Ecological Health, Ministry of Education, College of Natural Resources and Environmental Science, Zhejiang University, Hangzhou, China.
House dust mite (HDM) allergens are one of the most important causes of allergenic diseases in the indoor environment. The World Health Organization (WHO) has defined risk thresholds for Group I HDM allergens as a concentration of 2 and 10 μg/mL in dust for producing asthma risk and polar asthma attacks, respectively. Continuing exposure to high concentrations of HDM allergens greatly increases the risk of developing allergic diseases.
View Article and Find Full Text PDFAm J Geriatr Psychiatry
February 2025
Department of Psychiatry (AJCS, EJG), Leiden University Medical Center, Leiden, The Netherlands; Health Campus The Hague (EJG), Department of Public Health & Primary Care, Leiden University Medical Center, Leiden, The Netherlands. Electronic address:
Background: The prevalence of depressive symptoms, apathy, and cognitive decline increases with age. Understanding the temporal dynamics of these symptoms could provide valuable insights into the early stages of cognitive decline, allowing for more timely and effective treatment and management.
Methods: Participants from the Prevention of Dementia by Intensive Vascular Care (preDIVA) trial cohort with baseline and ≥3 follow-up measurements were included, with a median of 7.
Res Social Adm Pharm
March 2025
Department of Primary Care and Medical Education, Institute of Medicine, University of Tsukuba, 1-1-1, Tennodai, Tsukuba, Ibaraki, 305-8575, Japan. Electronic address:
Background: Deprescribing by physicians based on the suggestions of community pharmacists is useful to ensure medication safety. Pharmacist-led deprescribing is not always implemented smoothly because of communication gaps between physicians and pharmacists. Our previous study found that assertiveness, as a communication style, is associated with pharmacist-initiated prescription changes for medication safety; however, its association with community pharmacist-led deprescribing is unclear.
View Article and Find Full Text PDFDisabil Health J
March 2025
School of Psychology, The University of Adelaide, SA, 5000, Australia.
Background: The importance of health literacy in personal health management is widely recognised in the general population, yet remains poorly understood in some patient groups, including people with spinal cord injury or disorder (SCI/D).
Objectives: The systematic review had two objectives: (1) to determine the health literacy levels of individuals with SCI/D, and (2) to identify facilitators and barriers to developing health literacy in this group.
Methods: Seven databases (CINAHL, Embase, Emcare, ProQuest, PsycINFO, PubMed, and Web of Science) were searched from inception, with an updated search completed on January 21, 2025.
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