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FFR-Guided Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Diabetes.
JAMA Cardiol
March 2025
Stanford University School of Medicine, Stanford University, Stanford, California.
Importance: Outcomes in patients with diabetes after fractional flow reserve (FFR)-guided percutaneous coronary intervention (PCI) using current-generation drug-eluting stents (DES) compared with coronary artery bypass grafting (CABG) are unknown.
Objectives: To investigate the relative treatment effect of PCI vs CABG according to diabetes status with respect to major adverse cardiac and cerebrovascular events (MACCE) at 3 years and to evaluate the impact of the SYNTAX score.
Design, Setting, And Participants: This is a prespecified subgroup analysis of the FAME (Fractional Flow Reserve vs Angiography for Multivessel Evaluation) 3 trial, an investigator-initiated, randomized clinical trial conducted at 48 centers worldwide.
COMPARISON OF STENT GEOMETRY ACHIEVED BY DIFFERENT SIDE-BRANCH BALLOONING TECHNIQUES FOR BIFURCATION PROVISIONAL STENTING: THE CRABBIS TRIAL.
JACC Cardiovasc Interv
March 2025
Department of Cardiovascular and Pulmonary Sciences, Università Cattolica del Sacro Cuore, Rome, Italy; Department of Cardiovascular Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy. Electronic address:
Background: "Stepwise provisional stenting" is the most adopted approach for percutaneous coronary interventions (PCI) in bifurcation lesions. During these procedures, side-branch (SB) may deserve treatment, but the best ballooning technique is still undetermined.
Objectives: To compare the stent configurations obtained by two SB ballooning sequences after the main vessel (MV) stent implantation: proximal-optimization-technique (POT)+kissing-balloon-inflation+final POT (PKP) versus POT+isolated-SB-dilation+final POT (PSP).
30-Day DAPT in Patients at High Bleeding Risk Undergoing PCI With Biodegradable-Polymer Sirolimus-Eluting Ultra-Thin Stent.
Catheter Cardiovasc Interv
March 2025
Department of Cardiology, Maasstad Hospital, Rotterdam, the Netherlands.
Background: There is limited evidence on the safety and efficacy of biodegradable-polymer sirolimus-eluting ultra-thin stent (BP-SES) in patients at high bleeding risk (HBR) undergoing percutaneous coronary intervention (PCI).
Aims: This study aims to evaluate the clinical outcomes of HBR patients treated with BP-SES and ≤ 30-day dual antiplatelet therapy (DAPT) regimen.
Methods: A systematic review was conducted to identify relevant studies involving HBR patients who underwent PCI with BP-SES (Supraflex Cruz).
Study on the potential clinical significance of subclinical stent edge effects after drug-eluting stent implantation.
Sci Rep
March 2025
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu Province, 210006, China.
Unlabelled: The edge effect (EE) of isolated restenosis at one or both ends of a stent is not reduced by drug-eluting stent (DES). The purpose of the study was to investigate the long-term outcome of 1-year subclinical DES-EE (sDES-EE), which was defined as any reduction in the minimal lumen area (MLA) at stent edge without any evidence of clinical ischemia. A total of 252 patients were enrolled from one of our previous randomized controlled studies, who were detected by optical coherence tomography (OCT) immediately after DES implantation and 1 year later.
View Article and Find Full Text PDFSuccessful Rescue Treatment for Acute Ischemic Stroke Due to Intracranial Atherosclerotic Disease Using the Neuroform Atlas Stent.
Cureus
February 2025
Neurosurgery, Fukuoka University Hospital, Fukuoka, JPN.
The recanalization rate of endovascular therapy for acute ischemic stroke in intracranial atherosclerotic disease (ICAD) is inferior to that of cardiogenic stroke. This case study presents the long-term outcomes of a patient who underwent implantation of the Neuroform Atlas stent for the treatment of intracranial carotid artery stenosis, despite repeated re-occlusions after percutaneous transluminal angioplasty (PTA). A 75-year-old woman was transferred to our hospital with aphasia.
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