Para-testicular fibrous pseudotumors (PFP) are rare benign reactive lesions comprising of 6 % of para-testicular masses. Often misdiagnosed as malignant due to clinical and radiological overlap, they are frequently treated with aggressive surgery. We report a case of a 70-year-old male with a left inguinal swelling diagnosed post-orchidectomy as PFP. Histopathology revealed collagen-rich fibrotic tissue with lymphoplasmacytic infiltrates and IgG4-positive plasma cells. While PFP treatment requires surgical resection, testicle-sparing procedures with intraoperative frozen section assessment may prevent unnecessary orchidectomy. Further studies are needed to establish diagnostic protocols and explore the association between PFP and IgG4-related diseases.
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http://dx.doi.org/10.1016/j.eucr.2025.102989 | DOI Listing |
Urol Case Rep
March 2025
Department of General Surgery, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.
Para-testicular fibrous pseudotumors (PFP) are rare benign reactive lesions comprising of 6 % of para-testicular masses. Often misdiagnosed as malignant due to clinical and radiological overlap, they are frequently treated with aggressive surgery. We report a case of a 70-year-old male with a left inguinal swelling diagnosed post-orchidectomy as PFP.
View Article and Find Full Text PDFBMC Cancer
December 2019
Division of Urology, Department of Surgery, Kaohsiung Veterans General Hospital, No.386, Ta-Chung 1st Rd, 81362, Kaohsiung, Taiwan.
Background: Ganglioneuromas (GNs) are composed of mature ganglion cells and Schwann cells with a fibrous stroma; GNs are most often observed in children and young adults. The majority of non-cranial GNs are located in the retroperitoneum and posterior mediastinum. Other reported rare sites include the adrenal gland, small intestine, colon and urinary bladder.
View Article and Find Full Text PDFArch Ital Urol Androl
December 2016
Clinica Urologica, Scuola di Specializzazione in Urologia, Università Politecnica delle Marche, Ancona.
Introduction: Testicular benign tumors are very rare (< 5%). Testicular Angiofibroma (AF) is one of those, however the gold standard of treatment and follow-up is still unclear.
Case Report: A 47 years-old man with only one functioning testis was referred to our clinic for a palpable right testicular mass and atrophic contralateral testis.
Indian J Pathol Microbiol
July 1998
Anand Institute of Laboratory Medicine, Bangalore, India.
Twenty two patients with tumours or tumour-like conditions of the para-testicular region (PTR) were diagnosed over a 5 year period. Of these, 16 (73%) were benign with only one true neoplasm (papillary cystadenoma). The tumour-like conditions were comprised of 6 cases of adenomatous hyperplasia of epididymis, 4 cases of spermatic granuloma, 2 cases each of spermatocele and nodular-fibrous proliferation and one mesothelial cyst.
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