Angiomyolipomas (AMLs) represent the most common benign solid renal tumors. The frequency of their detection in the general population is increasing owing to advances in imaging technology. The objective of this review is to discuss computed tomography (CT) and magnetic resonance imaging findings for both typical and atypical renal AMLs, along with their associated complications. AMLs are typically defined as solid triphasic tumors composed of varying amounts of dysmorphic and tortuous blood vessels, smooth muscle components and adipose tissue. In an adult, a classical renal AML appears as a solid, heterogeneous renal cortical mass with macroscopic fat. However, up to 5% of AMLs contain minimal fat and cannot be reliably diagnosed by imaging. Fat-poor AMLs can appear as hyperattenuating masses on unenhanced CT and as hypointense masses on T2WI; other AMLs may be isodense or exhibit cystic components. Hemorrhage is the most common complication, and AMLs with hemorrhage can mimic other tumors, making their diagnosis challenging. Understanding the variable and heterogeneous nature of this neoplasm to correctly classify renal AMLs and to avoid misdiagnosis of other renal lesions is crucial.
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http://dx.doi.org/10.4329/wjr.v17.i2.104282 | DOI Listing |
Endocr Pathol
March 2025
Division of Oncology, Department of Medicine I, Medical University of Vienna, Vienna, Austria.
Neuroendocrine tumors (NET) of the lung constitute a rare entity of primary lung malignancies that often exhibit an indolent clinical course. Epigenetics-related differences have been described previously for lung NET, but the clinical significance remains unclear. In this study, we performed genome-wide methylation analysis using the Infinium MethylationEPIC BeadChip technology on FFPE tissues from lung NET treated at two academic centers.
View Article and Find Full Text PDFPsychiatry Clin Neurosci
March 2025
Department of Neuropsychiatry, School of Medical Sciences, University of Fukui, Fukui, Japan.
Aim: Previous studies have reported atypical sensory responses in individuals with autism spectrum disorder (ASD) and their implications for social touch. Although adults with ASD often report discomfort with being touched by others, their preferences for the physical properties of objects are less well understood. In a prior study, we observed that, in typically developed (TD) adults, compliance (a physical correlate of softness) increased tactile pleasantness for deformable surfaces up to levels comparable to those of human body parts.
View Article and Find Full Text PDFHCA Healthc J Med
February 2025
Texas College of Osteopathic Medicine, Forth Worth, Texas.
Background: Ovarian or adnexal torsions occur when an ovary rotates around one of the supporting ligaments, often the infundibulopelvic (IP) ligament. This rotation can cause the blood flow to the ovary to be hindered, and this decrease in perfusion can often present as adnexal pain, nausea, and vomiting. A significant risk factor for developing an ovarian torsion is the presence of an ovarian mass, such as a cyst.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
February 2025
Otolaryngology - Head and Neck Surgery, Patna Medical College, Patna, Bihar India.
Head and neck swellings encompass a broad range of differential diagnoses, often necessitating comprehensive clinical and diagnostic evaluations to reach an accurate diagnosis. Cysticercosis, a parasitic infection caused by the larval form of Taenia solium, typically affects neural and extraneural regions. Although neural manifestations are well-documented, extraneural cysticercosis in the head and neck is rare and can mimic neoplastic and inflammatory conditions, posing diagnostic challenges.
View Article and Find Full Text PDFCureus
February 2025
Gastroenterology and Hepatology, Baylor Scott & White All Saints Medical Center, Fort Worth, USA.
Intraductal papillary mucinous neoplasms (IPMNs) are a prevalent subtype of pancreatic cystic lesions, especially among individuals with liver cirrhosis. Intraductal papillary neoplasms of the bile duct (IPNBs) differ in histopathology based on the location and cellular variability in each location. Intrahepatic IPNBs are less aggressive than the extrahepatic variant, highlighting its heterogeneity and complexity.
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