In order to improve the accuracy of concentration detection in turbid media, this study proposes a solution concentration detection method based on a variable-angle wedge-shaped sample cell. Each angle of the wedge-shaped sample cell corresponds to a specific optical path combination. By measuring at multiple wedge angles, we can expand a variety of optical path combinations, providing more information about the turbid media. In this study, transmission light intensity distribution characteristics of phantom solutions were collected at wedge angles ranging from 10 to 45°, with a 5° interval, and a multipath combination detection model was constructed. By analyzing the distribution characteristics of the transmission light intensity along the gradient direction, multipath combination information was fused, and a calibration model was constructed using partial least-squares regression. The results show that, compared to the detection method using a fixed-angle to construct multiple optical paths, the multipath combination method effectively improves the accuracy of concentration detection in turbid media, with a prediction set correlation coefficient (Rp) reaching 0.995. Therefore, this study proposes a new method to enhance the accuracy of turbid media detection by utilizing scattering characteristics through the construction of a multipath combination model by varying the wedge-shaped sample cell angles.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886670 | PMC |
| http://dx.doi.org/10.1021/acsomega.4c09130 | DOI Listing |
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