Mpox, formerly known as monkeypox, is a zoonotic virus of the genus, with recent outbreaks of Clade I and Ib in Central Africa presenting a considerable global health threat. This study reviews current Mpox immunization approaches, focusing on the MVA-BN, LC16-KMB, and OrthopoxVac vaccines. MVA-BN vaccination has been successful in lowering infection risks, particularly in high-risk individuals and is widely used in the USA. LC16-KMB is recommended by the World Health Organization for prevention in afflicted regions. OrthopoxVac, a newer vaccination authorized in Russia, provides wide protection. Adapting vaccination approaches based on epidemiology in particular areas is critical for minimizing Mpox outbreaks.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11889354 | PMC |
| http://dx.doi.org/10.1016/j.imj.2025.100166 | DOI Listing |
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