In development the interrelationship between physiology and anatomy is challenging as learners must appreciate how physiological processes and anatomical structures change over time. In addition, the dynamic relationships between structure and function are often concealed largely due to the inaccessibility of the embryo in higher-order organisms. This makes it difficult for students to appreciate normal intricate balances or interpret physiological consequences of developmental disruptions to normal embryological development. In this paper, the applicability of the chick embryo model for use in practical classes is explored as students can observe developmental processes firsthand within a controlled environment. Practical approaches involved in developing the chick embryo model are described and then expanded to demonstrate how the model can be utilized to showcase the cardiovascular system development as an example. The model is further adapted to explore the effect of teratogenic disruptors such as ethanol on normal cardiovascular processes and highlights how prenatal alcohol exposure results in cardiovascular anomalies associated with Fetal Alcohol Syndrome (FAS), such as septal defects and altered cardiac physiology. In class, students can directly observe chick development from 0-to-8 days post-fertilisation. Measurable outcomes, such as comparisons in septal thickness, are calculated, while questions and answers to stimulate student discussion around functional changes and the impact of maternal consumption of alcohol are provided as resource material. The method outlined uses relatively inexpensive materials and requires little space, making it a cost-effective educational tool to support student learning of embryology.
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http://dx.doi.org/10.1152/advan.00195.2024 | DOI Listing |
Poult Sci
March 2025
Department of Poultry Science, Mississippi State University, Mississippi State, MS 39762, USA. Electronic address:
The effects of a reduction in incubation temperature, made to accommodate higher levels of embryonic heat production, on the post hatch body temperature and somatic characteristics of Ross 708 broilers were determined. Incubation temperature treatments (TRT) were a standard (STRT, 37.5 °C) and a lower (LTRT, 35.
View Article and Find Full Text PDFSci Rep
March 2025
Institute of Anatomy, University of Bern, Bern, Switzerland.
Microbeam Radiation Therapy is a preclinical form of spatially fractionated radiation therapy that utilizes synchrotron X-rays to deliver highly heterogeneous dose distributions at a micrometric scale. This radiation scheme has been shown to facilitate the induction of controlled and reversible vascular permeability, enhancing treatment efficacy of systemic therapeutic agents. Despite the promising preclinical results, translating microbeam SFRT to the clinic has been hindered by a reliance on synchrotron sources that operate at dose rates orders of magnitude greater than what is possible with clinical machines.
View Article and Find Full Text PDFAdv Physiol Educ
March 2025
Centre for Biomedical Sciences Education, Queen's University Belfast, Belfast, United Kingdom.
In development the interrelationship between physiology and anatomy is challenging as learners must appreciate how physiological processes and anatomical structures change over time. In addition, the dynamic relationships between structure and function are often concealed largely due to the inaccessibility of the embryo in higher-order organisms. This makes it difficult for students to appreciate normal intricate balances or interpret physiological consequences of developmental disruptions to normal embryological development.
View Article and Find Full Text PDFAnat Histol Embryol
March 2025
Department of Anatomy, Veterinary Medicine, Selcuk University, Konya, Turkey.
The aim of this study was to determine the embryotoxic and teratogenic effects of doxycycline on chicken embryos. Eggs placed in the incubator were checked with an ovoscope on the 7th day, and a total of 210 fertile chicken eggs were randomly divided into 7 groups. Doxycycline was applied to the experimental groups at 2500, 1250, 625, 312, and 156 μg/50 μL volumes, respectively.
View Article and Find Full Text PDFDev Biol
March 2025
Instituto de Ciências Biomédicas, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. Electronic address:
During skeletal muscle development catabolic and anabolic events are finely orchestrated by several heat shock proteins (HSP). HSP90 are molecular chaperones which play an essential role in maintaining cellular homeostasis. Although HSP90 proteins have been widely studied in cancer cells, their role during skeletal myogenesis has not been completely explored.
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