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Extracted of polysaccharides from the roots of Eremurus persicus bioss plant / polyvinyl alcohol: Design and characterization of cellular scaffold for cell culture applications.
Int J Biol Macromol
February 2025
Research Institute for Biotechnology and Bioengineering, Isfahan University of Technology, Isfahan 84156-83111, Iran. Electronic address:
Biomaterial-based cell scaffolds are one of the interesting cases in tissue engineering. It provides a substrate for repairing and growing different cells which facilitates the healing process of injuries. Therefore, its ingredients must be completely biocompatible and nontoxic to cells.
View Article and Find Full Text PDFThe Effect of Heat and Fermentation Treatments of Soybean Meal on Performance, Immune System, Microbial Population, Intestinal Morphology, and PepT1 Gene Expression in Broiler Chickens.
J Anim Sci
February 2025
Department of Animal Science, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.
We investigated the effects of replacing raw soybean meal (RSM) with autoclaved soybean meal (ASBM) and fermented soybean meal by Lactobacillus plantarum (FSBMLP) and Bacillus pumilus (FSBMBP) on the performance, microbial population, intestinal morphology, immune system, and PepT1 gene expression in broiler chickens. One-day-old male Ross 308 broiler chicks (n=800) were utilized in a fully randomized design featuring eight treatments and five replicates, and each replicate consisted of 20 chicks. The experimental treatments included: 1) a control group ((RSM)-based diet), 2) a basal diet + ASBM, 3) a basal diet + 2% FSBMLP, 4) basal diet + 4% FSBMLP, 5) basal diet + 6% FSBMLP, 6) basal diet + 2% FSBMBP, 7) basal diet + 4% FSBMBP, and 8) basal diet + 6% FSBMBP.
View Article and Find Full Text PDFDifferential antibiosis predisposes mice to Campylobacter jejuni infection: Deeper insights into the impact of the gut microbiota composition in colonization resistance.
Eur J Microbiol Immunol (Bp)
February 2025
1Gastrointestinal Microbiology Research Group, Institute of Microbiology, Infectious Diseases and Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, 12203 Berlin, Germany.
Conventional laboratory mice are protected from oral Campylobacter jejuni infection due to colonization resistance (CR) mediated by their host-specific gut microbiota. Here, we used differential effects of distinct antibiotics on gut microbiota composition to identify microbial groups associated with CR against C. jejuni.
View Article and Find Full Text PDFComparative effects of arsenic trioxide and chemotherapy on Chk1 and CDC25 gene expression in gastric cancer cells AGS and MKN45: a potential therapeutic strategy.
Mol Biol Rep
February 2025
Research Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
Background: Gastric cancer (GC) remains a significant global health burden, particularly in East Asia, where it is a leading cause of cancer-related morbidity and mortality. Despite advancements in chemotherapy, the development of chemoresistance continues to undermine the efficacy of standard treatments such as Docetaxel and Oxaliplatin. Arsenic trioxide (ATO) has emerged as a potential therapeutic agent capable of overcoming resistance by targeting DNA repair mechanisms, particularly through the downregulation of Checkpoint Kinase 1 (Chk1).
View Article and Find Full Text PDFRecent advances in bioactive materials: Future perspectives and opportunities in oral cancer biosensing.
Talanta
May 2025
Department of Chemical Engineering, National Taiwan University of Science and Technology, Taiwan. Electronic address:
Bioactive materials and biosensing technologies are emerging as pivotal tools in the early detection and management of oral cancer, a disease characterized by high morbidity and mortality rates. Recent advancements in nanotechnology have facilitated the development of innovative biosensors that utilize bioactive materials for non-invasive diagnostics, particularly through salivary analysis. These biosensors, including electrochemical, optical, and molecular types, target specific biomarkers such as DNA, RNA, and proteins associated with oral cancer.
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