Mimicked by the structure of dimethyl sulfoxide propionate (DMSP), a novel zwitterion monomer of -methylacryloyl -methyl l-cysteine methyl sulfonium salt (NMASMCMS) was synthesized and characterized for the first time through three steps using l-cysteine as a starting material. Poly(NMASMCMS) brushes were constructed on PET sheets via surface-initiated reversible addition-fragmentation chain-transfer (SI-RAFT) polymerization. The physical and chemical structures were characterized by water contact angle (WCA), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), and atomic force microscopy (AFM). The polymer brush grafted sheets (PET-B) had good hydrophilicity and high lubricity. Moreover, PET-B sheets exhibited excellent antifouling and hemocompatible properties with low protein adsorption, bacterial adhesion, platelet adhesion, and hemolysis.
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