Objective: (1) To evaluate the ability of western performance horses diagnosed with chondromalacia to return to performance; Specifically, the relationship between the grade of chondromalacia and the horses' ability to resume work; (2) To determine the impact of postoperative therapy on clinical outcomes.
Study Design: Retrospective case series.
Animals: Horses (n = 34).
Methods: Records of western performance horses with lameness localized to the stifle that underwent subsequent arthroscopy with chondromalacia as the most significant diagnosis were reviewed. Chondromalacia was surgeon-graded as slight, mild, moderate, or marked. Three evaluated categories of postoperative intra-articular therapy included: (1) bone marrow derived mesenchymal stem cells, (2) equine amniotic allograft product or (3) none. Outcome was defined as returning to previous level of work on a numeric scale (1-10).
Results: Chondromalacia and its degree of severity and focal vs. diffuse distribution identified arthroscopically did not show a significant association (p = .54, .40, respectively) or correlation (p = .18; R-value: 0.27) with the ability to return to athletic performance. The type of postoperative intra-articular therapy did not have any association with the horse returning to athletic work (p = .53).
Conclusion: A statistically significant association between severity, distribution or subsequent postoperative therapy for stifle chondromalacia and the ability to return to work was not observed.
Clinical Significance: Compared to previously published reports, this study demonstrated a 74% more favorable prognosis for returning to some level of athletic work despite only 44% of horses returning to their previous level of performance.
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http://dx.doi.org/10.1111/vsu.14196 | DOI Listing |
Clin Transplant
March 2025
Division of Cardiac Surgery, CardioVascular Center, Tufts Medical Center, Boston, Massachusetts, USA.
Background: This study aims to analyze the patient characteristics, clinical outcomes, and contemporary trends concerning type A aortic dissection (TAAD) in previous recipients of abdominal solid organ transplantation (ASOT) in the United States.
Methods: The National Inpatient Sample was queried to identify all patients aged ≥18 with TAAD and a history of ASOT (TAAD-ASOT) between 2002 and 2015Q3 using ICD-9 diagnosis and procedure codes. Baseline characteristics and in-hospital outcomes were compared between TAAD-ASOT patients and TAAD patients without a history of ASOT (TAAD-non-ASOT).
Eur J Cardiothorac Surg
March 2025
Division of Thoracic Surgery, Department of Surgery, Taipei Veterans General Hospital, ; Taipei City, Taiwan.
Objectives: To assess the prognostic impact of adequate lymphadenectomy and determine the optimal nodal assessment for different clinical stages of lung cancer.
Methods: We retrospectively reviewed 1214 patients with clinical stage I-III non-small cell lung cancer who had preoperative PET/CT and curative surgery (2006-2017). Patients were categorized based on whether they had adequate [R0] or inadequate lymphadenectomy [R(un)].
Interdiscip Cardiovasc Thorac Surg
March 2025
Division of Cardiac Surgery, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Objectives: Differences in inflammatory responses between men and women may contribute to sex disparities in cardiac surgery outcomes. We investigated how sex differences influence systemic inflammatory response syndrome (SIRS) and adverse outcomes after cardiac surgery.
Methods: A single-center retrospective cohort study of patients undergoing cardiac surgery from 2018 to 2020 was performed.
Sci Transl Med
March 2025
Hagey Laboratory for Pediatric Regenerative Medicine, Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.
Postoperative abdominal adhesions are the leading cause of bowel obstruction and a cause of chronic pain and infertility. Adhesion formation occurs after 50 to 90% of abdominal operations and has no proven preventative or treatment strategy. Abdominal adhesions derive primarily from the visceral peritoneum and are composed of polyclonally proliferating tissue-resident fibroblasts.
View Article and Find Full Text PDFBackground: The perioperative management of patients undergoing cardiac surgery is highly complex and involves numerous factors. There is a strong association between cardiac surgery and perioperative complications. The Brazilian Surgical Identification Study (BraSIS 2) aims to assess the incidence of death and early postoperative complications, identify potential risk factors, and examine both the demographic characteristics of patients and the epidemiology of cardiovascular procedures.
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