Airborne optical imaging can flexibly obtain the intuitive information of the observed scene from the air, which plays an important role of modern optical remote sensing technology. Higher resolution, longer imaging distance, and broader coverage are the unwavering pursuits in this research field. Nevertheless, the imaging environment during aerial flights brings about multi-source dynamic interferences such as temperature, air pressure, and complex movements, which forms a serious contradiction with the requirements of precision and relative staticity in optical imaging. As the birthplace of Chinese optical industry, the Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP) has conducted the research on airborne optical imaging for decades, resulting in rich innovative achievements, completed research conditions, and exploring a feasible development path. This article provides an overview of the innovative work of CIOMP in the field of airborne optical imaging, sorts out the milestone nodes, and predicts the future development direction of this discipline, with the aim of providing inspiration for related research.
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http://dx.doi.org/10.1038/s41377-025-01776-3 | DOI Listing |
Exp Eye Res
March 2025
Department of Ophthalmology, University of Washington, Seattle, Washington; Roger and Angie Karalis Johnson Retina Center, Seattle, Washington. Electronic address:
Age-related macular degeneration (AMD), a leading cause of vision loss among older adults, affecting more than 200 million people worldwide. With no cure currently available and a rapidly increasing prevalence, emerging approaches such as artificial intelligence (AI) and machine learning (ML) hold promise for advancing the study of AMD. The effective utilization of AI and ML in AMD research is highly dependent on access to high-quality and reusable clinical data.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
March 2025
Senior Department of Orthopedics, The Fourth Medical Center of PLA General Hospital, Beijing 100142, China. Electronic address:
Vitamins are indispensable active components of the human body, and their abnormal levels are often closely related to various diseases. Therefore, searching for ultra-sensitive and accurate vitamin detection strategies is essential and significant for clinical examination and diagnosis. In this paper, multi-wavelength emission fluorescent nitrogen-doped carbon dots (N-doped CDs) were synthesized by a one-step solvothermal method using four-leaf green fluorescent extract, O-phenylenediamine, and β-cyclodextrin as the raw materials, and N, N-dimethylformamide as the solvent.
View Article and Find Full Text PDFPhys Med
March 2025
Department of Medical Physics, University of Wisconsin-Madison, Madison WI USA.
Purpose: Cherenkov imaging in radiation therapy provides key knowledge of the delivery of treatment plans, but light-tissue interactions alter the emitted spectral signal and cause the modeling of emission relative to dose in highly modulated treatment plans to be complex.
Methods: A 2-stage Monte Carlo approach to modeling Cherenkov emission was developed that leverages a traditional treatment planning system with an optical Monte Carlo simulation to provide a widely useable and efficient tool for modeling every beam control point for delivery interpretation of highly-modulated treatment plans. The emitted optical spectra were estimated for 6, 10, 15MV photon beams, 6 MeV electron beams, beam incidence in tissue, and square field sizes from 1 cm to 20 cm.
BMC Ophthalmol
March 2025
Department of Ophthalmology, Copenhagen University Hospital Rigshospitalet, Valdemar Hansens vej, 13, 2600, Glostrup, Denmark.
Background: Semaglutide, a glucagon-like peptide-1 receptor agonist, is increasingly used worldwide for its cardiometabolic benefits. However, it has recently been associated with nonarteritic anterior ischemic optic neuropathy (NAION). This report presents four clinical cases and explores a possible association.
View Article and Find Full Text PDFSci Rep
March 2025
Department of Ophthalmology, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheongju, Korea.
Intravitreal anti-vascular endothelial growth factor (VEGF) injections are essential for treating neovascular age-related macular degeneration (nAMD), but patient responses vary significantly, complicating standardized regimens. This study identifies early optical coherence tomography (OCT) biomarkers and best-corrected visual acuity (BCVA) as predictors of injection frequency in a one-year treat-and-extend (T&E) regimen to optimize individualized treatment. A retrospective analysis of treatment-naïve nAMD patients receiving intravitreal aflibercept was conducted.
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