Asthma is a chronic lung disease that occurs repeatedly and is hardly cured. Clinical studies have shown that acupuncture can effectively relieve asthma-related symptoms and is an ideal measure to treat asthma. The paper reviews the clinical and mechanism researches of acupuncture for asthma reported in China and other countries in recent 5 years, so as to provide the relevant evidences for the further study on asthma. The results showed that the mechanism of acupuncture in treatment of asthma may be related to modulating immune cytokines, ameliorating iron metabolism disorder, regulating the expression of neurotransmitter and receptor, promoting eosinophile apoptosis, inhibiting the expression of matrix metalloproteinase-9 and matrix metalloproteinase inhibitor-1, suppressing the expression of the related proteins and genes in type 2 innate lymphoid cells, inhibiting the signal pathways such as transforming growth factor-β1/Smad, mitogen-activated protein kinase, phosphatidylinositol 3-kinase/protein kinase B, signal transducer and activator of transcription, and nuclear factor-κB. Accordingly, the airway inflammatory response can be suppressed, the airway hyperreactivity be reduced, and the airway remodeling be relieved.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.13702/j.1000-0607.20230637 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Inflammatory Signatures in VEXAS Syndrome, Myelodysplasia Cutis, and Sweet Syndrome.
JAMA Dermatol
March 2025
Service de Dermatologie et Allergologie, Faculté de Médecine, Sorbonne Université, Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, Paris, France.
Importance: VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) is a monogenic disease caused by UBA1 somatic variants in hematopoietic progenitor cells, mostly involving adult men. It is associated with inflammatory-related symptoms, frequently involving the skin and hematological disorders. Recently described myelodysplasia cutis (MDS-cutis) is a cutaneous manifestation of myelodysplasia in which clonal myelodysplastic cells infiltrate the skin.
View Article and Find Full Text PDFFan therapy for breathlessness - how do you do it and why?
Curr Opin Support Palliat Care
March 2025
Wolfson Palliative Care Research Centre, University of Hull, Hull, East Yorkshire, UK.
Purpose Of The Review: This review summarises high-level evidence for fan therapy and adds a commentary on the relatively-neglected question of how to optimise benefits based on qualitative evidence, clinical experience and broader research and theory.
Recent Findings: Recent high-level evidence suggests the fan reduces time to recovery from episodic breathlessness rather than reduces daily levels over a longer period. Lower grade evidence suggests the fan can also help people increase their physical activity.
Lifei Qingchang Tang attenuates acute lung injury the NF-κB and MAPK signaling pathways.
J Asian Nat Prod Res
March 2025
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou510120, China.
Acute lung injury (ALI) has high morbidity and mortality. Lifei Qingchang Tang (LFQCT), a traditional Chinese medicine, has antioxidant and anti-inflammatory properties but its mechanism in ALI remains unclear. , LFQCT reduced intracellular Ca, ROS, and NO in LPS-induced RAW 264.
View Article and Find Full Text PDFHGF-DPSCs ameliorate asthma by regulating CCR1 Th2 cells responses in mice pulmonary mucosa.
Cytotherapy
February 2025
Health Management Institute, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, China. Electronic address:
Asthma, a prevalent allergic disease affecting approximately 300 million individuals globally, remains a significant public health challenge. Mesenchymal stromal cells (MSCs) and hepatocyte growth factor (HGF), both recognized for their immunomodulatory properties, hold therapeutic potential for asthma. However, their precise mechanisms remain underexplored.
View Article and Find Full Text PDFA novel dominant-negative variant of IRF8 in a mother and son: Clinical, phenotypic and biological characteristics.
J Allergy Clin Immunol
March 2025
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minn. Electronic address:
Background: The few reported patients with pathogenic IRF8 variants have manifested 2 distinct phenotypes: (1) an autosomal recessive severe immunodeficiency with significant neutrophilia and absence of or significant decrease in monocytes and dendritic cells and (2) a dominant-negative form with only a decrease in conventional type 2 dendritic cells (cDC2s) and susceptibility to mycobacterial disease.
Objectives: Genetic testing of a child with persistent EBV viremia identified a novel IRF8 variant: c.1279dupT (p.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!