Although there have been several reports of drug-induced pneumonitis caused by herbal medicines in recent years, herbal medicine-induced diffuse alveolar hemorrhage (DAH) is rare. We herein report two cases of DAH associated with herbal medicines. Patient 1 developed dyspnea and hemoptysis after receiving jidabokuippo. Patient 2 developed a fever and dyspnea after taking otsuji-to. Both patients exhibited severe respiratory failure, and bronchoalveolar lavage revealed bloody fluid that confirmed the diagnosis of DAH. In both patients, discontinuation of herbal medicines and corticosteroid therapy resulted in significant improvement. These cases highlight the potential risks of DAH associated with herbal medicines.
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http://dx.doi.org/10.2169/internalmedicine.4960-24 | DOI Listing |
PLoS One
March 2025
Food Technology and Process Engineering, Oda Bultum University, Chiro, Ethiopia.
This study investigates the synthesis and characterization of Plant-Ag-graphene nanocomposites through a combination of spectroscopic and microscopic techniques, the nanocomposites were formed by catalyzing silver nanoparticles with plant extracts, and the resulting structures were analyzed using advanced instrumentation. In the FTIR analysis, distinctive peaks were observed at 3340 cm⁻1 (O-H stretching), 1740 cm⁻1 (C = O stretching), and 1050 cm⁻1. When compared to silver nanoparticles, the nanocomposites exhibited altered peak intensities, indicating modifications in chemical bonding.
View Article and Find Full Text PDFMetab Brain Dis
March 2025
Department of Biochemistry, Faculty of Sciences, University of Uyo, Uyo, Nigeria.
Kindling is an experimental-induced seizure consistent with epilepsy disease, a chronic neurological disorder characterised by spontaneous and repeated seizures. This disease is associated with oxidative stress, and most therapeutic strategies against epilepsy aim at improving the antioxidant defence mechanism in the brain. However, prolonged usage and associated adverse side effects limit antiepileptics, warranting natural antioxidant patronage.
View Article and Find Full Text PDFMycorrhiza
March 2025
INRAE, Institut Agro Dijon, Université de Bourgogne, Agroécologie, Dijon, France.
Plant-microorganism interactions underlie many ecosystem roles, in particular the enhancement of plant nutrition through mutualistic relationships, such as the arbuscular mycorrhizal symbiosis that affects a large proportion of land plants. The establishment of this interaction induces a wide range of signaling pathways in which lipids, and particularly sterols, may play a central role. However, their supported functions are poorly known.
View Article and Find Full Text PDFArch Dermatol Res
March 2025
Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui Province, 230032, China.
This study aimed to evaluate the utilization of complementary and alternative medicine (CAM) among Chinese patients with inflammatory arthritis (IA), the types of CAM used, and the factors associated with its use. This cross-sectional study was conducted at the Department of Rheumatology and Immunology at the First Affiliated Hospital of Anhui Medical University. Data were collected from 503 IA patients using self-administered questionnaires and electronic medical records.
View Article and Find Full Text PDFEur J Nutr
March 2025
Nestlé Institute of Health Sciences, Nestlé Research, Lausanne, Switzerland.
Purpose: In the current study we evaluated a blend of ingredients containing mulberry leaf extract (to lower postprandial glucose of the evening meal), tryptophan (facilitator of the sleep initiation) to benefit sleep initiation and quality in adults with self-reported difficulties with sleep initiation.
Methods: Forty-three adults aged between 25 and 50 years enrolled in a randomized, crossover, double-blind, controlled trial. Participants received standardized meals with a glycemic load of 55 ± 10% and were assigned to receive treatment comprising a combination of mulberry leaf extract (750 mg), whey protein containing 120 mg tryptophan, zinc (1.
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