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Circulating Blood-Based Proteins in Psychopathology and Cognition: A Mendelian Randomization Study.
JAMA Psychiatry
March 2025
Institute of Behavioral Science, Feinstein Institutes for Medical Research, Manhasset, New York.
Importance: Peripheral (blood-based) biomarkers for psychiatric illness could benefit diagnosis and treatment, but research to date has typically been low throughput, and traditional case-control studies are subject to potential confounds of treatment and other exposures. Large-scale 2-sample mendelian randomization (MR) can examine the potentially causal impact of circulating proteins on neuropsychiatric phenotypes without these confounds.
Objective: To identify circulating proteins associated with risk for schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD) as well as cognitive task performance (CTP).
Novel, multimodal, simulation practice with evolving case scenario for teaching familial communications in undergraduate medical training.
Med Teach
March 2025
Centre for Healthcare Simulation, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
There is a growing recognition of the importance of familial involvement in patient care. In Asian societies, communications with patients' families for routine medical updates and shared decision-making are considered part-and-parcel of clinical practice. Yet, training in familial communications has remained, by and far, a neglected aspect of conventional communications skills training in the medical curriculum, despite distinctive nuances in the communications approach.
View Article and Find Full Text PDFMulti-level barriers to equitable postpartum permanent contraception.
Womens Health (Lond)
March 2025
Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Background: There are several barriers to fulfillment of desired postpartum permanent contraception (PC). Prior research has primarily focused on the federal Medicaid sterilization policy as a barrier to PC; however, other barriers need to be examined.
Objectives: To explore the levels and intersections of barriers to postpartum PC that exist external to the Medicaid policy.
Determinants of weight gain in pregnant women with hyperemesis gravidarum in Dire Dawa administration, Eastern Ethiopia: An unmatched case-control study.
Womens Health (Lond)
March 2025
Department of Laboratory Technology Science, School of Medicine, College of Medicine and Health Sciences, Dire Dawa University, Dire Dawa, Ethiopia.
Background: Adequate gestational weight gain affects birth outcomes and increases the risk of non-communicable diseases later in life. Weight gain in pregnant Ethiopian women with hyperemesis gravidarum has not been investigated comprehensively.
Objective: To assess the determinants of weight gain in pregnant women with hyperemesis gravida in Dire Dawa Administration, Eastern Ethiopia.
First successful use of translocated autologous great saphenous vein to the upper arm for hemodialysis access in Vietnam: A 3-year follow-up case report.
J Vasc Access
March 2025
Department of Vascular Surgery, Duc Tin Clinic, Ho Chi Minh, Vietnam.
The rising global incidence of kidney failure has increased the demand for long-term hemodialysis, which requires reliable vascular access. While arteriovenous fistulas (AVFs) are typically preferred, alternative approaches are needed when autogenous options are exhausted. The use of translocated autologous saphenous vein (SV) conduits has been predominantly documented in developed countries but rarely employed in developing nations, including Vietnam.
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