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Infection by Clonally Related Isolates: The Role of Drinking Water.
Am J Respir Crit Care Med
March 2025
The University of Queensland, Children's Health Research Centre, Faculty of Medicine , Brisbane, Queensland, Australia.
Rationale: group bacteria (MABS) cause lethal infections in people with chronic lung diseases. Transmission mechanisms remain poorly understood; the detection of dominant circulating clones (DCCs) has suggested potential for person-to-person transmission.
Objectives: This study aimed to determine the role of drinking water in the transmission of MABS.
Geographical and temporal variations of serogroups and clonal types of involved in culture-confirmed invasive meningococcal disease in Canada, 2015-2023.
J Med Microbiol
March 2025
Vaccine Preventable Bacterial Diseases, Science, Reference and Surveillance Directorate, National Microbiology Laboratory Branch, Pubic Health Agency of Canada, Winnipeg, Manitoba, Canada.
Invasive meningococcal disease (IMD) is a nationally notifiable illness in Canada due to its potential severity and transmissibility. Vaccination strategies differ by province/territory and are informed by changes in the antigenic characteristics of circulating strains. Though IMD statistics are tracked at a provincial/territorial level, there is a lack of published data characterizing trends in the epidemiology of this disease at a national level.
View Article and Find Full Text PDFAntibiotic resistance and molecular characterization of clinical Shigella spp. isolated from hospitals located in Tehran and Qazvin cities, Iran.
BMC Res Notes
March 2025
Department of Biology, East Tehran Branch, Islamic Azad University, Tehran, Iran.
Objective: This research aims to investigate the epidemiology and genetic changes of Shigella species in the cities of Qazvin and Tehran from 2003 to 2023, with a focus on assessing antibiotic resistance among the isolates. This study is based on the analysis of 80 Shigella isolates, which were obtained from patients' feces.
Results: Using pulsed-field gel electrophoresis (PFGE) as the primary typing method, the isolates were classified into 13 distinct clusters, revealing a dominant pattern that has persisted for over twenty years.
Virulence factors, molecular characteristics, and resistance mechanisms of carbapenem-resistant Pseudomonas aeruginosa isolated from pediatric patients in Shanghai, China.
BMC Microbiol
March 2025
Department of Nosocomial Infection Control, The Clinical Laboratory, Clinical Microbiology Laboratory, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Background: The investigation into virulence factors, clinical and molecular characteristics, and resistance mechanisms of carbapenem-resistant Pseudomonas aeruginosa (CRPA) in pediatric populations is currently inadequate.
Purpose: This study aimed to investigate the virulence factors, clinical and molecular characteristics, and resistance mechanisms of 135 CRPA isolates in Shanghai, China.
Methods: Analysis of virulence-associated genes and multilocus sequence typing (MLST) provided epidemiological and molecular insights into the isolates.
Increasing polymyxin resistance in clinical carbapenem-resistant Klebsiella pneumoniae strains in China between 2000 and 2023.
Commun Med (Lond)
March 2025
Department of Clinical Laboratory, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.
Background: Development of polymyxin resistance in carbapenem-resistant Klebsiella pneumoniae (CRKP) poses a severe challenge to public health. Here we aimed to perform a retrospective study of prevalence and molecular characteristics of polymyxin-resistant CRKP strains.
Methods: 4455 clinical CRKP strains from 18 provinces in China during 2000 to 2023 were collected.
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