Clam digging has a long history in Hong Kong, but unregulated clam digging activities depletes clam populations and threatens the ecosystem. Population genomics is useful to unravel the connectivity of clams at different geographical locations and to provide necessary conservation measures; and yet, only limited number of clams in Hong Kong have genomic resources. Here, we present chromosomal-level genome assemblies for two clams commonly found in Hong Kong, Anomalocardia flexuosa and Meretrix petechialis, using a combination of PacBio HiFi and Omni-C reads. For A. flexuosa, we assembled the genome into 19 pseudochromosomes with a genome size of 1.09 Gb (scaffold N50 = 58.5 Mb), and BUSCO scores of 94.4%. A total of 20,881 gene models were also predicted using the transcriptomes generated in this study. For M. petechialis, the genome was mainly assembled into 19 pseudochromosomes with a genome size of 1.04 Gb (scaffold N50 = 53.5 Mb), and BUSCO scores of 95.7%. A total of 20,084 gene models were also predicted using the transcriptomes generated in this study. The two new genomic resources established in this study will be useful for further study of biology, ecology, and evolution of clams, as well as setting up a foundation for evidence-informed decision making in conservation measures and implementation.
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http://dx.doi.org/10.1038/s41597-025-04748-9 | DOI Listing |
Med Law Rev
January 2025
Edinburgh Law School, University of Edinburgh, Edinburgh EH8 9YL, United Kingdom.
Patients harmed by medical mishaps are often driven to litigation because of a lack of apologies and candour rather than a desire for monetary compensation. Despite attempts at clinical negligence reform, patients continue to receive unsatisfactory responses. Physicians have cited fears of legal liability as a key reason for withholding apologies.
View Article and Find Full Text PDFJ Mater Chem B
March 2025
Clinical Translational Research Center of Aggregation-Induced Emission, School of Medicine, The Second Affiliated Hospital, School of Science and Engineering, Shenzhen Institute of Aggregate Science and Technology, The Chinese University of Hong Kong, Shenzhen (CUHK-Shenzhen), Guangdong 518172, P. R. China.
MXenes, a novel class of two-dimensional materials, have recently emerged as promising candidates for biomedical applications due to their specific structural features and exceptional physicochemical and biological properties. These materials, characterized by unique structural features and superior conductivity, have applications in tissue engineering, cancer detection and therapy, sensing, imaging, drug delivery, wound treatment, antimicrobial therapy, and medical implantation. Additionally, MXene-based composites, incorporating polymers, metals, carbon nanomaterials, and metal oxides, offer enhanced electroactive and mechanical properties, making them highly suitable for engineering electroactive organs such as the heart, skeletal muscle, and nerves.
View Article and Find Full Text PDFPublic Health Nutr
March 2025
Department of Geography, Faculty of Social Science, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
China has dedicated significant efforts to preventing obesity, but the rising prevalence of overweight and obesity remains a pressing public health issue. Therefore, unique solutions are required to address this challenge in China. As a research priority, the food environment plays a pivotal role in addressing overweight and obesity.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
March 2025
Central South University, School of Metallurgy and Enviroment, No. 932, Lushan Road,, Changsha city, Hunan Province, 410083, Changsha, CHINA.
Activated by the Li-O-Li configuration with nonbonding O2p state (lO2p), anionic redox reaction (ARR) in Li-rich layered oxides (LLOs) contributes to additional capacity but exhibits significant irreversibility, leading to severe surface oxygen loss. Herein, surface nonbonding oxygen state (SNBOS) is regulated by the integrated surface structure engineering to suppress surface oxygen loss and enhance the reversibility of ARR. On the outermost layer, the conversion of layered structure into a LiLaO2 layer and spinel phase structure eliminates lO2p, thereby preventing the activation of ARR and suppressing side reaction between electrolyte and oxidized oxygen ions.
View Article and Find Full Text PDFFront Pediatr
February 2025
Division of Paediatric Surgery & Paediatric Urology, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Purpose: Prostatic utricle cyst (PUC) is known to be associated with hypospadias. We aimed to investigate the prevalence of PUC in children with proximal hypospadias by cystoscopy, and risk of symptom development after hypospadias repair.
Methods: We retrospectively reviewed the records of patients who underwent 2-stage repair for proximal hypospadias and had cystoscopy for PUC assessment over the period of January 2017-September 2022.
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