In China, the drug treatment of many cancer pain patients is obviously affected by people's lack of knowledge and confidence, and cancer pain symptoms fail to be effectively controlled. This retrospective case-control study explored the effect of application of structured education management in standardized treatment of cancer pain. Eligible cancer pain patients from June 2022 to April 2023 were selected as the control group. The intervention group was selected from May 2023 to December 2023. Control group received analgesic treatment according to three-step analgesia method, the intervention group received structured cancer pain education intervention on the basis of the treatment for control group. The level of pain control disorders, total effective rate of pain relief and the frequency of pain outbreak, equivalent morphine consumption, and incidence of adverse events were compared between the two groups at enrollment and 2 weeks after. After treatment, the pain control disorder scores and NRS scores in the two groups were lower than that before treatment, and intervention group were lower than that in control group. The total effective rate of pain relief in intervention group was higher than that in control group. The total equivalent morphine dosage in the intervention group was lower than that in the control group. The incidence of constipation, nausea, vomiting, and fatigue in the intervention group was significantly lower than that in the control group, but there was no significant difference in the incidence of rash. Clinical pharmacist-led structured education can significantly improve therapeutic effect on cancer pain and reduce the adverse reactions.
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http://dx.doi.org/10.1007/s13187-025-02600-7 | DOI Listing |
JMIR Res Protoc
March 2025
Paseo de los Encomendadores, Faculty of Health Sciences, University of Burgos, Burgos, Spain.
Background: Breast cancer is the second most common cancer in women worldwide. Treatments for this disease often result in side effects such as pain, fatigue, loss of muscle mass, and reduced quality of life. Physical exercise has been shown to effectively mitigate these side effects and improve the quality of life in patients with breast cancer.
View Article and Find Full Text PDFJ Oncol Pharm Pract
March 2025
Department of Pharmacy Management, Faculty of Pharmacy, Gazi University, 06330, Ankara, Türkiye.
BackgroundOpioid therapy is a critical component in managing pain in palliative care, where pharmacists' specialised expertise is crucial in ensuring quality care for patients. This systematic review aims to document available evidence on pharmacist interventions and their impact on optimising opioid therapy for pain management in palliative care patients.MethodsWe searched Medline (OVID), Embase (OVID), APA PsycINFO and Cochrane Central Register of Controlled Trials (CENTRAL) for relevant articles published from the beginning to 31 December, 2022.
View Article and Find Full Text PDFJ Cancer Surviv
March 2025
Department of Health Sciences, University of Central Florida College of Health Professions and Sciences, 4364 Scorpius Street, Orlando, FL, USA.
Purpose: This study analyzed the long-term effects of cancer on the health-related quality of life (HRQOL) of older breast cancer survivors for 10 years, including a control group to distinguish between the impacts of cancer treatment and aging.
Methods: The SEER-MHOS data resource was used in the analysis. Cases were 674 older women diagnosed with breast cancer in 1998-2015 at age 65 and older and participated in Medicare Health Outcomes Survey within 24 months before their cancer diagnosis and at least once within 10 years of post-diagnosis.
Pain Ther
March 2025
Unit of Internal Medicine, Fondazione Policlinico Universitario Campus Bio-Medico, Via Alvaro del Portillo, 200, 00128, Rome, Italy.
Introduction: Opioid-induced constipation (OIC) is a common side effect of chronic opioid therapy that significantly impacts quality of life and healthcare costs. Naldemedine, a peripherally acting mu-opioid receptor antagonist, has shown efficacy in treating OIC. However, real-world evidence on naldemedine use in the United States is limited, particularly in older adults.
View Article and Find Full Text PDFSupport Care Cancer
March 2025
Department of Breast Surgery, Jiangsu Province Hospital, No. 368 Jiangdong North Road, Gulou District, Nanjing City, 210000, Jiangsu Province, China.
Objective: To investigate the effects of a combined Gua Sha and myofascial release approach on upper limb dysfunction in patients with breast cancer and axillary web syndrome (AWS).
Methods: In this prospective case series study, 30 patients with breast cancer diagnosed with AWS post-surgery were recruited. Participants underwent a 12-week intervention combining Gua Sha and myofascial release techniques.
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