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http://dx.doi.org/10.1186/s40360-025-00891-6 | DOI Listing |
BMC Pharmacol Toxicol
March 2025
Department of Cardiology, National Heart and Lung Institute, Imperial College London, London, UK.
Zhonghua Jie He He Hu Xi Za Zhi
March 2025
Bronchial asthma (asthma) is a common chronic respiratory disease. Standardized diagnosis, treatment and effective clinical management are critical to improving asthma control, improving patients' quality of life, and reducing the disease burden. Based on the latest evidence-based research from both domestic and international references, the Asthma Group of the Chinese Thoracic Society has revised the " ()".
View Article and Find Full Text PDFHypertension
February 2025
Department of Obstetrics and Gynecology, University of Alberta, Edmonton, Canada. (A.A.d.O., F.S., M.E.G., R.K., A.Q., C.-L.M.C., S.T.D.).
Background: Excessive hypercholesterolemia in pregnancy increases the risk of preeclampsia, though the mechanisms remain unclear. We recently showed that uterine artery function is impaired in hypercholesterolemia-preeclampsia via activation of the TLR4 (toll-like receptor 4)/PGHS1 (prostaglandin H synthase 1) pathway. Low-dose aspirin lowers preeclampsia risk in high-risk pregnancies by inhibiting PGHS1, but its effects in hypercholesterolemia-preeclampsia pregnancies are not known.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!