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| http://dx.doi.org/10.1186/s12889-024-21258-2 | DOI Listing |
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Special Issue on CDS Failures: A Case Study: Optimizing CDS for Pediatric Oncology Trials by Transitioning from Interruptive to Passive Alerts.
Appl Clin Inform
March 2025
Department of Pediatrics, Division of Pediatric Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada.
Background: Many children with cancer are treated as part of interventional clinical trials. Ensuring that the correct chemotherapy treatment plan is used is paramount.
Objectives: The objectives of this report were to: (1) highlight the initial design of a clinical decision support (CDS) tool that was intended to help ensure the correct matching of research studies to research chemotherapy medications, (2) discuss the issues identified with the CDS tool, and (3) review the redesign of the tool that was done to overcome the issues identified.
Knee alignment and patella shape are not associated with persistence of patellofemoral pain.
J ISAKOS
March 2025
Erasmus Medical Center Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam. Electronic address:
Introduction: Patellofemoral pain (PFP) is suggested as a precursor of patellofemoral osteoarthritis (PFOA) later in life. This hypothesis is based on shared risk factors for both diseases, such as deviating alignment parameters. In patients with PFOA, certain 2D alignment parameters and 3D shape variations are associated with the progression of PFOA.
View Article and Find Full Text PDFUnplanned Return to the Operating Room After Cataract Surgery.
Am J Ophthalmol
March 2025
Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address:
Objective: To determine the rate of unplanned return to operation room (OR) within 90 days of cataract surgery and to identify the most common pre-operative and intraoperative risk factors.
Design: Retrospective case-control study.
Subjects And Controls: Patients aged >= 40 years undergoing cataract surgery at the Wilmer Eye Institute between 2019-2022 with at least 90 days of postoperative follow-up were included.
Mediating effects of gastroesophageal reflux disease and smoking behavior on the relationship between depression and chronic obstructive pulmonary disease: Trans-ethnic Mendelian randomization study.
J Affect Disord
March 2025
Department of Thoracic Surgery, Suzhou Hospital of Integrated Traditional Chinese and Western Medicine, Suzhou 215101, China. Electronic address:
Background: This study seeks to elucidate the association between depression and the risk of chronic obstructive pulmonary disease (COPD) by Mendelian randomization (MR) analysis, motivated by prior observational studies indicating a potential link between these conditions.
Methods: Data from individuals of European (EUR) and East Asian (EAS) ancestries diagnosed with major depressive disorder (MDD) were selected for analysis. The primary method utilized was inverse variance weighted (IVW) method, supplemented by a series of sensitivity analyses and false discovery rate (FDR) corrections.
[Is previable rupture of membranes an independent neonatal prognostic factor from the gestational age at birth?].
Gynecol Obstet Fertil Senol
March 2025
Département mère-enfant, Institut mutualiste Montsouris, Paris, France.
Objective: Compare, at the same gestational age at birth, survival without severe neonatal morbidity among live-born infants after previable premature rupture of membranes (PROM) occurring before 22 weeks of gestation (WG) versus at or after 22 weeks.
Methods: Retrospective study conducted in a tertiary care referral center between 2016 and 2021, including live births between 23 and 36 weeks + 6 days after PROM. Only live-born infants with neonatal resuscitation care were included.
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