In an era of increasing sophistication and frequency of cyber threats, securing Internet of Things (IoT) networks has become a paramount concern. IoT networks, with their diverse and interconnected devices, face unique security challenges that traditional methods often fail to address effectively. To tackle these challenges, an Intrusion Detection System (IDS) is specifically designed for IoT environments. This system integrates a multi-faceted approach to enhance security against emerging threats. The proposed IDS encompasses three critical subsystems: data pre-processing, feature selection and detection. The data pre-processing subsystem ensures high-quality data by addressing missing values, removing duplicates, applying one-hot encoding, and normalizing features using min-max scaling. A robust feature selection subsystem, employing Synergistic Dual-Layer Feature Selection (SDFC) algorithm, combines statistical methods, such as mutual information and variance thresholding, with advanced model-based techniques, including Support Vector Machine (SVM) with Recursive Feature Elimination (RFE) and Particle Swarm Optimization (PSO) are employed to identify the most relevant features. The classification subsystem employ two stage classifier namely LightGBM and XGBoost for efficient classification of the network traffic as normal or malicious. The proposed IDS is implemented in MATLAB by using TON-IoT dataset with various performance metrics. The experimental results demonstrate that the proposed SDFC method significantly enhances classifier performance, consistently achieving higher accuracy, precision, recall, and F1 scores compared to other existing methods.
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http://dx.doi.org/10.1038/s41598-025-91663-z | DOI Listing |
Biometrics
January 2025
Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States.
SARS-CoV-2-infected individuals have reported a diverse collection of persistent and often debilitating symptoms commonly referred to as long COVID or post-acute sequelae of SARS-CoV-2 (PASC). Identifying PASC and its subphenotypes is challenging because available data are "negative-unlabeled" as uninfected individuals must be PASC negative, but those with prior infection have unknown PASC status. Moreover, feature selection among many potentially informative characteristics can facilitate reaching a concise and easily interpretable PASC definition.
View Article and Find Full Text PDFJ Med Internet Res
March 2025
Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Background: Hypertension is a major global health issue and a significant modifiable risk factor for cardiovascular diseases, contributing to a substantial socioeconomic burden due to its high prevalence. In China, particularly among populations living near desert regions, hypertension is even more prevalent due to unique environmental and lifestyle conditions, exacerbating the disease burden in these areas, underscoring the urgent need for effective early detection and intervention strategies.
Objective: This study aims to develop, calibrate, and prospectively validate a 2-year hypertension risk prediction model by using large-scale health examination data collected from populations residing in 4 regions surrounding the Taklamakan Desert of northwest China.
JAMA Dermatol
March 2025
Department of Surgery, Arthur J.E. Child Comprehensive Cancer Centre, University of Calgary, Calgary, Alberta, Canada.
Importance: There is a need to identify the best performing risk prediction model for sentinel lymph node biopsy (SLNB) positivity in melanoma.
Objective: To comprehensively review the characteristics and discriminative performance of existing risk prediction models for SLNB positivity in melanoma.
Data Sources: Embase and MEDLINE were searched from inception to May 1, 2024, for English language articles.
Chem Rec
March 2025
University of Leuven, KU Leuven), LOMAC Celestijnenlaan 200F, B-3001, Leuven, Belgium.
Photosynthesis in plants has inspired photochemical reactions in organic chemistry. Synthetic organic chemists always seek cost-effective, operationally simple, averting the use of toxic and difficult-to-remove metallic catalysts, atom economical, and high product purity in organic reactions. In the last few decades, the use of light as a catalyst in organic reactions has increased exponentially as literature has exploded with examples, particularly by using toxic and expensive metal complexes, photosensitizers like organic dyes, hypervalent iodine, or by using inorganic semiconductors.
View Article and Find Full Text PDFChemistry
March 2025
Laboratoire de Chimie Supramoléculaire, Institut de Science et d'Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, 8 allée Gaspard Monge, BP 70028, F-67000, Strasbourg Cedex, France.
The conjugation-driven stability and reactivity of bis-imine formation from the reaction of substituted aromatic aldehydes and amines bearing electron donor and acceptor groups were studied in two approaches involving aldehydes and amines with the substituents either conjugated (para position) or non-conjugated (meta position) to the reacting functional groups. The bis-imine from the reaction of a bis-amine (B) with different types of aldehydes (A) constituted an ABA module, whereas the reaction of bis-aldehydes with different amines resulted in a BAB module. The competitive reactions were also studied for a specified bis-amine (B1 or B2) in similar conditions with a mixture of different aldehydes, and the time-dependent generations of dynamic covalent libraries were followed.
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