Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s11095-025-03839-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Integrating ePROMs: A Key Opportunity for England's National Cancer Plan.
J Cancer Policy
March 2025
Brighton and Sussex Medical School, University of Brighton and University of Sussex.
Mechanism-Based Middle-Range Theories: Using Realist Syntheses to Reconcile Specificity to Context and Generalizability.
Qual Health Res
March 2025
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.
Realist synthesis is a recognized methodological approach to evidence synthesis to inform evidence-based health policy and practice. The implicit assumption behind research synthesis is that the evidence it generates should be generalizable--drawing broad inferences from specific observations. While this understanding is generally shared among social scientists, tensions exist between having generalizable evidence and how this evidence can be useful in specific contexts.
View Article and Find Full Text PDFGenomic differentiation and SNP variation reveal local adaptations to eastern Mediterranean environmental conditions in wild radishes.
Ann Bot
March 2025
Institute of Plant Sciences, Agricultural Research Organization, Rishon LeZion 7505101, Israel.
Background And Aims: Morphological differences between the two genetically close wild radishes, Raphanus raphanistrum and R. pugioniformis, include differences in fruit structure that influence their dispersal ability and within population spatial structure. Here, we tested within- and among-populations genetic variation, hypothesizing that (i) short-distance dispersal of heavy fruits in R.
View Article and Find Full Text PDFSex Disparities in P53 Regulation and Functions: Novel Insights for Personalized Cancer Therapies.
Cells
February 2025
Istituto di Genetica Molecolare Luigi Luca Cavalli-Sforza, Consiglio Nazionale delle Ricerche (IGM-CNR), 20133 Pavia, Italy.
Epidemiological studies have revealed significant sex differences in the incidence of tumors unrelated to reproductive functions, with females demonstrating a lesser risk and a better response to therapy than males. However, the reasons for these disparities are still unknown and cancer therapies are generally sex-unbiased. The tumor-suppressor protein p53 is a transcription factor that can activate the expression of multiple target genes mainly involved in the maintenance of genome stability and tumor prevention.
View Article and Find Full Text PDFThe Tailored Activity Program (TAP), an intervention for people living with dementia (PLWD) and their caregivers, has been shown to reduce behavioral symptoms for PLWD and caregiver burden. While TAP is proven as an evidence-based practice (EBP), it has yet to be implemented at scale. The Department of Veterans Affairs (VA) has prioritized the Age-Friendly Health System (AFHS) initiative, providing an opportunity to test implementation of TAP in a complex healthcare system.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!