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Rapidly progressive mitral valve disease from non-bacterial thrombotic endocarditis to mitral stenosis in systemic lupus erythematosus: a case report.
Eur Heart J Case Rep
March 2025
Division of Cardiology, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8555, Japan.
Background: Libman-Sacks endocarditis), a non-bacterial thrombotic endocarditis (NBTE) linked to systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS), typically causes valve regurgitation and embolism but can rarely mimic rheumatic mitral stenosis (MS).
Case Summary: This case involves a 59-year-old woman with a history of APS and SLE who presented with worsening dyspnoea and congestive heart failure. Initially, severe mitral regurgitation (MR) due to NBTE resolved with vitamin K antagonist therapy, yet she subsequently developed significant MS with commissural fusion, a rheumatic-like feature.
Introducing the use of AngioVac in nonbacterial thrombotic endocarditis: a systematic review.
Future Cardiol
March 2025
Department of Medicine, Jacobi Medical Center/New York City Health and Hospitals Corporation, Bronx, NY, USA.
Introduction: Nonbacterial thrombotic endocarditis (NBTE) involves vegetations on heart valves without active bloodstream infection. The AngioVac device, a vacuum-based aspiration system commonly used for infective endocarditis, has potential in managing NBTE, particularly in patients unsuitable for surgery. This study systematically reviews the literature to evaluate AngioVac's effectiveness in reducing vegetations in NBTE.
View Article and Find Full Text PDFNonbacterial Thrombotic Endocarditis (NBTE) Treated With Crizotinib in Lung Adenocarcinoma Harboring ROS-1 Rearrangement: Two Case Report and Review of Literature.
Clin Lung Cancer
February 2025
Medical Oncology Department, Hospital Universitario Ramón y Cajal, Alcalá University, Madrid, Spain.
Nonbacterial Thrombotic Endocarditis of a Mitral Prosthesis After Warfarin, Enoxaparin, and Apixaban Failure.
JACC Case Rep
March 2025
Heart and Vascular Institute, Milton S. Hershey Medical Center, Hershey, Pennsylvania, USA.
Nonbacterial thrombotic endocarditis (NBTE) is an uncommon condition that carries significant morbidity and an in-hospital mortality rate of up to 36%. Involvement of a prosthetic valve with NBTE is even more rare. We present a case of prosthetic mitral valve NBTE that manifested 5 months after surgical mitral valve replacement.
View Article and Find Full Text PDFEmbolic Stroke Unveiling Lung Cancer: A Case of Cancer-Associated Non-bacterial Thrombotic Endocarditis.
Cureus
February 2025
Neurology, Hospital Vila Franca de Xira, Vila Franca de Xira, PRT.
We discuss the case of a 71-year-old male with various comorbidities who presented to the Emergency Department for prostration and gait abnormalities. Neurological assessment and imaging studies revealed a multi-territorial ischemic stroke. Further investigation identified a cardiac mass, raising suspicion of non-bacterial thrombotic endocarditis (NBTE), after ruling out infectious causes.
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