Purpose: Chiari malformation type 2 (CMII) is a herniation of anatomical structures of the posterior fossa due to myelomeningocele (MMC), the most common neural tube defect. Most patients with MMC exhibit radiological signs of CMII. The study aimed to evaluate radiological parameters of the posterior fossa in patients undergoing surgery for CMII, with the goal of establishing structural indications for surgical treatment to prevent clinical manifestations and life-threatening symptoms.
Methods: The study included all constitutive patients with CMII diagnosed between 2016 to 2018. The following measurements were taken and analyzed for associations: size of the fourth ventricle, the McRae's line, the depth of tonsillar herniation, the amount of cerebrospinal fluid (CSF) at the C0 level, the presence of syringomyelia, hydrocephalus, ventriculoperitoneal shunt (VPS) implantation, and supracerebellar cistern.
Results: The length of McRae's line and the depth of tonsillar herniation were strongly positively correlated. There was a negative relationship between the length of McRae's line and the amount of CSF at the C0 level. There was a strong positive correlation between depth of tonsillar herniation and hydrocephalus. MMC and VPS implantation were associated with a larger depth of tonsillar herniation.
Conclusion: The depth of the tonsillar herniation may not be the most viable finding influencing operative indication due to its dependency on the length of the McRae's line. A small amount of CSF at the level of foramen magnum also should not necessarily be considered an early sign of syringomyelia. Ventriculoperitoneal shunt implantation seems not to influence the depth of tonsillar herniation.
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http://dx.doi.org/10.1016/j.wneu.2025.123853 | DOI Listing |
World Neurosurg
March 2025
Department of Children Neurosurgery, Jagiellonian University Medical College, Kraków Poland.
Purpose: Chiari malformation type 2 (CMII) is a herniation of anatomical structures of the posterior fossa due to myelomeningocele (MMC), the most common neural tube defect. Most patients with MMC exhibit radiological signs of CMII. The study aimed to evaluate radiological parameters of the posterior fossa in patients undergoing surgery for CMII, with the goal of establishing structural indications for surgical treatment to prevent clinical manifestations and life-threatening symptoms.
View Article and Find Full Text PDFEur J Dermatol
October 2024
Otorhinolaryngology-Head and Neck Surgery, Peking University Third Hospital, Peking University, Beijing, Beijing 100000, China.
Palmoplantar pustulosis (PPP) is a chronic relapsing inflammatory disease of unknown aetiology characterized by erythema, scaling, and aseptic pustules, which pose a significant clinical, psychological, and economic burden to patients. Studies have shown that the tonsils play a key role in the exacerbation and pathogenesis of certain diseases. This paper systematically summarizes the evidence supporting the close association between tonsils and PPP, and proposes mechanisms by which tonsils may contribute to the pathogenesis of PPP.
View Article and Find Full Text PDFAnn Med Surg (Lond)
November 2024
Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Tishreen University, Lattakia, Syria.
Background: This study was designed to investigate the effectiveness and outcome of a new modification of the sphincter pharyngoplasty technique in the treatment of velopharyngeal insufficiency patients, with the determination of a specific dimension of velopharyngeal port and velum length of no hypernasality, snoring, and nasal regurgitation potential.
Materials And Methods: The study included 10 patients, who were suffering from consistent hypernasal speech after failure of conservative speech therapy. Clinical and radiographic measurements of the velopharyngeal port and velum length before and after surgery were done, with clinical patient follow-up to assess snoring and nasal regurgitation after surgery for 1, 6, and 12 months.
J Clin Neurosci
October 2024
Semmes-Murphey Clinic and Department of Neurosurgery, University of Tennessee, Memphis, TN, USA.
Cavernous malformations surrounding the fourth ventricle are challenging lesions to access and treat surgically owing to the complexity and eloquence of adjacent neural tissue [1] Long-standing practice included tissue transgression through the overlying cerebellar cortical surface of the hemisphere or vermis [1-3]. Using natural corridors such as tonsillobiventral fissure, cerebellomedullary fissure, and tonsillouvular fissure (TUF) offers elegant access to the fourth ventricle, avoiding traversing of neural tissue [4-7]. A 32-year-old male presented with headache, nausea, vomiting, double vision, and vertigo.
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