Introduction And Importance: Negative pressure pulmonary edema is a rare systemic complication ensuing from general anesthesia.
Case Presentation: In this report, a middle-aged male Who underwent V4 of vertebral artery stenting under general anesthesia, developed acute respiratory distress and a decrease inoxyhemoglobin saturation(SpO2). The condition was controlled after giving high concentration of oxygen assisted ventilation and sputum suction.
Clinical Discussion: The treatment process of this case suggested that negative pressure pulmonary edema is highly suspected when acute pulmonary edema occurs during the resuscitation of general anesthesia. The goal of the treatment is to keep the upper airway patent and correct hypoxemia.
Conclusion: NPPE is a clinically rare complication. The goal of the treatment is to keep the upper airway patent and correct hypoxemia.
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http://dx.doi.org/10.1016/j.ijscr.2025.110984 | DOI Listing |
Neurosurg Rev
March 2025
Department of Neurosurgery, Iwate Medical University School of Medicine, 2-1-1 Idaidori, Yahaba-cho, Yahaba, Iwate, 028-3694, Japan.
Despite successful management of pulmonary complication with fluid restriction protocol in aneurysmal subarachnoid hemorrhage (aSAH) patients treated with clazosentan, management of symptoms related to mucosal edema, such as diarrhea, stuffy nose, and difficulty in breathing, remains challenging. Hence, we investigated the effect of Goreisan shown to be effective in the treatment of symptoms related with mucosal edema in aSAH patients treated with clazosentan. Patients with aSAH who received clazosentan for vasospasm after aneurysm obliteration were prospectively enrolled in the study.
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February 2025
Pulmonary and Critical Care, BronxCare Health System, Bronx, USA.
Post-extubation stridor poses a significant challenge in critical care settings, often necessitating prompt intervention to prevent respiratory compromise and potential reintubation. This case report details the successful management of post-extubation stridor in a 55-year-old female patient with a complex medical history, using heliox therapy. Heliox, a gas mixture of helium and oxygen, has emerged as a novel therapeutic option in such scenarios, owing to its ability to reduce airway resistance and improve gas flow dynamics.
View Article and Find Full Text PDFPhytomedicine
March 2025
Division of Food Functionality Research, Korea Food Research Institute (KFRI), Wanju, 55365, South Korea; Department of Food Biotechnology, Korea University of Science and Technology (UST), Daejeon 34113, South Korea. Electronic address:
Background: Acute respiratory distress syndrome (ARDS) is a severe inflammatory disorder characterized by acute respiratory failure, alveolar barrier dysfunction, edema, and dysregulated alveolar macrophage-mediated pulmonary inflammation. Despite advancements in treatment strategies, the mortality rate in patients with ARDS remains high, ranging from 40-60 %. Current approaches are limited to supportive care, necessitating the exploration of effective therapeutic options such as suppressing broad inflammatory responses.
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February 2025
Department of Forensic Medicine and Toxicology, Rajendra Institute of Medical Sciences, Ranchi, IND.
Background: Histopathological examination, although mostly limited to scenarios where the cause of death is not readily apparent during the autopsy, possesses substantial significance in medico-legal autopsies conducted by medical boards, as it provides essential insights into both the causation and circumstances contributing to death. Diverse viewpoints persist about how histopathology is utilized in the context of medico-legal autopsies. This study examines the significance of histopathology in elucidating particular causes of death in medico-legal autopsies conducted by a medical board of doctors, with a predominant proportion of cases of custodial deaths.
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February 2025
Internal Medicine, Hospital da Senhora da Oliveira, Guimarães, PRT.
Tuberculosis (TB) is an infectious disease caused by acid-fast bacillus pertaining to the complex. Pulmonary TB is the most common presentation, resulting either from primary infection or reactivation of latent disease. In rare cases, wide dissemination of can occur, usually by hematogenous or lymphatic route, leading to multiorgan involvement and potentially life-threatening conditions known as disseminated TB.
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