Phys Rev Lett
Joint Quantum Institute, University of Maryland, College Park, Maryland 20783 USA.
Published: February 2025
The interplay between disorder and quantum interference leads to a wide variety of physical phenomena including celebrated Anderson localization-the complete absence of diffusive transport due to quantum interference between different particle trajectories. In two dimensions, any amount of disorder is thought to induce localization of all states at long enough length scales. In this Letter, we present an argument providing a mechanism for disrupting localization: by tuning the underlying curvature of the manifold on which diffusion takes place. We show that negative curvature manifolds contain a natural infrared cutoff for the probability of self-returning paths. We calculate the Cooperon-directly related to the weak-localization corrections to the conductivity-in hyperbolic space. It is shown that negative curvature leads to a rapid growth in the number of available trajectories a particle can coherently traverse in a given time, reducing the importance of interference effects and restoring diffusive behavior even in the absence of inelastic collisions. We further argue that on certain manifolds with variable curvature the hyperbolic regions dominate due to intermittency and arrest weak localization, which may be of relevance to two-dimensional materials due to surface roughness. This result may be amenable to experimental verification through the use of quantum simulators. Finally, we use results on mixed-curvature gravity by Zel'dovich to argue that our generic result on the absence of weak localization in two dimensions also applies to surfaces of mixed curvature, which may be of relevance to realistic experiments on weakly disordered metallic films on rough substrates.
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http://dx.doi.org/10.1103/PhysRevLett.134.076301 | DOI Listing |
Dent Mater
March 2025
Department of Conservative Dentistry and Periodontology, LMU University Hospital, LMU Munich, Goethestrasse 70, Munich 80336, Germany.
Objectives: The aim of this study was to examine the marginal seal of novel bioactive restorative materials and the material-related properties associated with bacterial microleakage.
Methods: Class II cavities prepared into human extracted teeth were restored with: Venus Diamond (VD) + selective enamel etching (SEE)/self-etching universal adhesive (SEA), ACTIVA BioACTIVE RESTORATIVE (AB) + SEE/SEA, Cention Forte (CF) + Cention Primer, Ketac Universal Aplicap (KU), EQUIA Forte HT (EF) and Surefil One (SO) and exposed to a cariogenic multi-species bacterial suspension for 7 days. Bacterial microleakage was visualized with a modified gram staining protocol and bacterial penetration depths were microscopically determined after sectioning the teeth.
J Phys Chem B
March 2025
Department of Chemistry, University of Rome Sapienza, Rome 00185, Italy.
We present a structural characterization of a low-transition-temperature mixture (LTTM), consisting of thymol and carvacrol, at an equimolar ratio. Carvacrol and thymol are natural regioisomers of terpenes. When combined at an equimolar ratio, they form a liquid mixture at room temperature, with supercooling capability and glass transition at ca.
View Article and Find Full Text PDFCancer Rep (Hoboken)
March 2025
UOC Haematology, ASL Viterbo-Santa Rosa Hospital, Viterbo, Italy.
Background: Multiple myeloma (MM) is more often characterized by clonal plasma cell proliferation restricted to the bone marrow. However, a small percentage of patients with MM develop extramedullary disease (EMD): this type of localization is found in 1.7%-4.
View Article and Find Full Text PDFWorld J Otorhinolaryngol Head Neck Surg
March 2025
Objectives: Enhanced recovery after surgery (ERAS) protocols for endoscopic sinus surgery (ESS) have not been widely implemented, and a critical review of ERAS recommendations and a comprehensive analysis of the supporting literature has not been undertaken. We describe an ESS ERAS protocol including key perioperative interventions for patients undergoing ESS and assess the available evidence.
Data Sources: A search was conducted of all relevant ERAS literature in otorhinolaryngology, anesthesia, and surgery using Medline (via PubMed), and Scopus.
Breast Cancer Res
March 2025
Centre for Experimental Cancer Medicine, Barts Cancer Institute, London, UK.
Background: The multicohort, open-label, phase 1b KEYNOTE-173 study was conducted to investigate pembrolizumab plus chemotherapy as neoadjuvant therapy for triple-negative breast cancer (TNBC). This exploratory analysis evaluated features of the tumor microenvironment that might be predictive of response.
Methods: Cell fractions from 20 paired samples collected at baseline and after one cycle of neoadjuvant pembrolizumab prior to chemotherapy initiation were analyzed by spatial localization (tumor compartment, stromal compartment, or sum of tumor and stromal compartments [total tumor]) using three six-plex immunohistochemistry panels with T-cell, myeloid cell, and natural killer cell components.
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