Case: We present an unusual case of metachronous multicentric giant cell tumor (GCT) of forearm bones in a 38-year-old male patient with an 8-year follow-up. The diagnosis was established by imaging and histopathology. He underwent multiple surgeries with extraperiosteal resection of lesions with free fibular grafts. No new lesion was detected in the last 3 years. When last seen, the patient was asymptomatic (apart from restricted supination). A literature review is also presented.
Conclusion: Metachronous multicentric GCT involving only the forearm bones is rare. A high index of suspicion is necessary to differentiate it from other polyostotic lesions.
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http://dx.doi.org/10.2106/JBJS.CC.24.00566 | DOI Listing |
Gan To Kagaku Ryoho
February 2025
Dept. of Gastroenterological Surgery, Akita City Hospital.
An 81-year-old man underwent a partial laparoscopic hepatectomy for tumors in the S7 segment of the liver and was diagnosed with moderately to poorly differentiated hepatocellular carcinoma(HCC). Two years and 10 months later, MRI identified a 10 mm tumor in the S8 segment of the liver, indicative of highly differentiated HCC. Colorectal endoscopy subsequently revealed a submucosal tumor in the transverse colon, with biopsy findings showing features similar to the previous HCC.
View Article and Find Full Text PDFJBJS Case Connect
January 2025
Department of Orthopaedic Surgery, Maulana Azad Medical College & Associated Lok Nayak Hospital, New Delhi, India.
Case: We present an unusual case of metachronous multicentric giant cell tumor (GCT) of forearm bones in a 38-year-old male patient with an 8-year follow-up. The diagnosis was established by imaging and histopathology. He underwent multiple surgeries with extraperiosteal resection of lesions with free fibular grafts.
View Article and Find Full Text PDFClin Genitourin Cancer
February 2025
Department of Urology, Comprehensive Cancer Centre Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.
Sci Rep
November 2024
Azienda Ospedale Università di Padova, via Giustiniani 2, Padua, 35128, Italy.
Lynch syndrome is rarely associated with rectal cancer (RC) and thus, metachronous RC has been scarcely investigated. This study aimed to analyze the mucosal immune microenvironment in sporadic and metachronous RC. We analyzed the mucosal immune microenvironment in the 25 metachronous RCs present in the IMMUNOREACT 1 and 2 multicentre observational studies (624 patients).
View Article and Find Full Text PDFGraefes Arch Clin Exp Ophthalmol
November 2024
Department of Ophthalmology, The Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Purpose: To characterise patterns of disease recurrence in idiopathic orbital myositis (IOM).
Methods: Multi-centre retrospective longitudinal study of IOM patients. Serial imaging was also analysed.
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