Case: We present an unusual case of metachronous multicentric giant cell tumor (GCT) of forearm bones in a 38-year-old male patient with an 8-year follow-up. The diagnosis was established by imaging and histopathology. He underwent multiple surgeries with extraperiosteal resection of lesions with free fibular grafts. No new lesion was detected in the last 3 years. When last seen, the patient was asymptomatic (apart from restricted supination). A literature review is also presented.

Conclusion: Metachronous multicentric GCT involving only the forearm bones is rare. A high index of suspicion is necessary to differentiate it from other polyostotic lesions.

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http://dx.doi.org/10.2106/JBJS.CC.24.00566DOI Listing

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