A 23-year-old male presented with a 6-month history of left eyelid swelling and a 2-week history of headaches following a road traffic accident. Examination revealed left eye proptosis (23 mm vs. 19 mm on the right, normal 16 mm), limited abduction of the right eye, incomplete closure of the right upper eyelid, and right facial nerve weakness. No relative afferent pupillary defect (RAPD) was noted. Musculoskeletal ultrasound of the left eyelid identified an elongated subcutaneous cystic lesion with intense vascularity, indicative of a vascular lesion. CT of the facial bones with 3D reconstruction revealed bilateral proptosis, dilated superior ophthalmic veins, and enlarged cavernous sinuses, consistent with bilateral carotid-cavernous fistulas (CCFs). Otomastoiditis with facial nerve canal dehiscence was also noted, suggesting facial nerve involvement. MRI brain and orbit with gadolinium contrast demonstrated multiple dilated tortuous vascular structures communicating with the cavernous sinuses, dilated bilateral superior ophthalmic veins (left > right), and left eye proptosis, consistent with high-flow fistulas. High-flow characteristics were supported by early arterial filling of the cavernous sinuses, retrograde venous drainage, and superior ophthalmic vein dilation on MR angiogram. Bilateral CCFs are rare, typically resulting from trauma, and often present with proptosis, cranial nerve deficits, and orbital symptoms. Fundus examination revealed engorged retinal veins and mild optic disc swelling in the left eye, consistent with venous stasis. Endovascular surgery is the gold standard for treatment; however, this patient was managed symptomatically with analgesics due to financial constraints. This case demonstrates the importance of imaging in diagnosis and highlights the challenges of managing CCFs in resource-limited settings.
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http://dx.doi.org/10.1007/s13760-025-02756-5 | DOI Listing |
J Med Microbiol
March 2025
Department of Ophthalmology, Kazakh-Russian Medical University, 71 Torekulov Str., 050000, Almaty, Republic of Kazakhstan.
Eye diseases are widespread all over the world and, if left untreated, can lead to blindness. The use of 0.05% cyclosporine A (CsA) solution for the treatment of dry eye causes a decrease in discomfort and pain and improves objective measures such as tear film breakdown time, Schirmer test results and Oxford scale scores due to its anti-inflammatory and immunomodulatory properties that contribute to improved tear film stability and tear production.
View Article and Find Full Text PDFWearable Technol
February 2025
Department of Human Centered Design, Cornell University, Ithaca, NY, USA.
Real-time measurement of head rotation, a primary human body movement, offers potential advantages in rehabilitating head or neck motor disorders, promoting seamless human-robot interaction, and tracking the lateral glance of children with autism spectrum disorder for effective intervention. However, existing options such as cameras capturing the entire face or skin-attached sensors have limitations concerning privacy, safety, and/or usability. This research introduces a novel method that employs a battery-free RFID tag-based wearable sensor for monitoring head orientation, as a substitute for the existing options like camera.
View Article and Find Full Text PDFBMC Ophthalmol
March 2025
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Sun Yat-sen University, Guangzhou, 510060, China.
Purpose: To compare the refractive outcomes and visual quality among different types of astigmatism following SMILE and evaluate effective optical zone (EOZ) features, decentration and their potential effects on visual quality.
Methods: This study included 101 left eyes of 101 patients who underwent SMILE. Patients were grouped according to astigmatism types (with-the-rule [WTR], against-the-rule [ATR] and oblique astigmatism) and decentered displacement (major axis > minor axis and major axis < minor axis).
Sci Rep
March 2025
Department of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau, Sant Quintí, 89, 08041, Barcelona, Spain.
Patients with Type 1 Diabetes (T1DM) have a higher risk of cardiovascular disease. This study used carotid ultrasound to identify subclinical carotid plaques and Optical Coherence Tomography (OCT) to evaluate ophthalmological markers as predictors of carotid plaque presence in 242 adults with T1DM, employing machine learning models for early risk assessment. Individuals with carotid plaques (N = 67) did not show significant differences in retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) and inner plexiform layer (IPL) complex compared to those without (N = 175).
View Article and Find Full Text PDFOphthalmic Genet
March 2025
W. K. Kellogg Eye Center, Department of Ophthalmology, University of Michigan, Ann Arbor, Michigan, USA.
Background: Neurofibromatosis is a neurocutaneous syndrome that predisposes individuals to a variety of tumors. In type 2, these typically do not present until early adulthood. We present a case of an unusual fundus lesion in neurofibromatosis type 2 (NF2) in a young child.
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